Evidence map›Paper›PMID 37498533›Full record

SynthesisEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin2023

Estimates of hepatitis B virus prevalence among general population and key risk groups in EU/EEA/UK countries: a systematic review.

Sandra Bivegete, Anna L McNaughton, Adam Trickey, Zak Thornton, Becky Scanlan, Aaron G Lim, Lina Nerlander, Hannah Fraser, Josephine G Walker, Matthew Hickman and 5 more

Abstract readSystematic Review
In one paragraph

Synthesis in Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. EuroHePP: The European Toolkit to Strengthen National Responses for the Elimination of Viral Hepatitis in Prisons.Liver international : official journal of the International Association for the Study of the Liver · 2026
    Review
  5. Review
  6. Article
  7. Review
  8. Article
  9. Use of the Workbook Method to estimate the prevalence of chronic hepatitis B infections in the European Union and European Economic Area, 2022.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2026
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Diagnosed Patients With Chronic Hepatitis B and Delta Virus in Italy in 2024: An Estimation From a National Real-World Database.Liver international : official journal of the International Association for the Study of the Liver · 2025
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Sandra BivegetePopulation Health Sciences, Bristol Medical School, University of Bristol, United Kingdom.
Anna L McNaughtonPopulation Health Sciences, Bristol Medical School, University of Bristol, United Kingdom.
Adam TrickeyPopulation Health Sciences, Bristol Medical School, University of Bristol, United Kingdom.
Zak ThorntonPopulation Health Sciences, Bristol Medical School, University of Bristol, United Kingdom.
Becky ScanlanPopulation Health Sciences, Bristol Medical School, University of Bristol, United Kingdom.
Aaron G LimPopulation Health Sciences, Bristol Medical School, University of Bristol, United Kingdom.
Lina NerlanderEuropean Centre for Disease Prevention and Control (ECDC), Stockholm, Sweden.
Hannah FraserPopulation Health Sciences, Bristol Medical School, University of Bristol, United Kingdom.
Josephine G WalkerPopulation Health Sciences, Bristol Medical School, University of Bristol, United Kingdom.
Matthew HickmanPopulation Health Sciences, Bristol Medical School, University of Bristol, United Kingdom.
Peter VickermanPopulation Health Sciences, Bristol Medical School, University of Bristol, United Kingdom.
Helen JohnsonEuropean Centre for Disease Prevention and Control (ECDC), Stockholm, Sweden.
Erika DuffellEuropean Centre for Disease Prevention and Control (ECDC), Stockholm, Sweden.
Ellen Brooks-PollockPopulation Health Sciences, Bristol Medical School, University of Bristol, United Kingdom.
Hannah ChristensenPopulation Health Sciences, Bristol Medical School, University of Bristol, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BackgroundThe burden of chronic hepatitis B virus (HBV) varies across the European Union (EU) and European Economic Area (EEA).AimWe aimed to update the 2017 HBV prevalence estimates in EU/EEA countries and the United Kingdom for 2018 to 2021.MethodsWe undertook a systematic review, adding to HBV prevalence estimates from an existing (2005-2017) database. Databases were searched for original English-language research articles including HBV surface antigen prevalence estimates among the general population, pregnant women, first-time blood donors (FTB), men who have sex with men (MSM), migrants and people in prison. Country experts contributed grey literature data. Risk of bias was assessed using a quality assessment framework.FindingsThe update provided 147 new prevalence estimates across the region (updated total n = 579). Median HBV prevalence in the general population was 0.5% and the highest was 3.8% (Greece). Among FTB, the highest prevalence was 0.8% (Lithuania). Estimates among pregnant women were highest in Romania and Italy (5.1%). Among migrants, the highest estimate was 31.7% (Spain). Relative to 2017 estimates, median prevalence among pregnant women decreased by 0.5% (to 0.3%) and increased by 0.9% (to 5.8%) among migrants. Among MSM, the highest estimate was 3.4% (Croatia). Prevalence among people in prison was highest in Greece (8.3%) and the median prevalence increased by 0.6% (to 2.1%).ConclusionsThe HBV prevalence is low in the general population and confined to risk populations in most European countries with some exceptions. Screening and treatment should be targeted to people in prison and migrants.

Indexed as

Hepatitis BHepatitis B, ChronicEuropean UnionFemaleHepatitis B virusHumansMalePregnancyPrevalenceRisk FactorsUnited KingdomEpidemiologyhepatitis B Virusprevalencerisk groupssystematic review

Identifiers

PMID37498533
PMCPMC10375838

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.