Evidence map›Paper›PMID 37501786›Full record

ReviewFrontiers in endocrinology2023

A new mutation in the

Valentina Mancioppi, Tommaso Daffara, Martina Romanisio, Giovanni Ceccarini, Caterina Pelosini, Ferruccio Santini, Simonetta Bellone, Simona Mellone, Alessio Baricich, Ivana Rabbone and 4 more

Open access · goldAbstract readReviewCase Reports
In one paragraph

Review in Frontiers in endocrinology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Severe Insulin Resistance Syndromes: Clinical Spectrum and Management.International journal of molecular sciences · 2025
    Review
  7. Article
  8. Article
  9. Insulin Delivery Technology for Treatment of Infants with Neonatal Diabetes Mellitus: A Systematic Review.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2024
    Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 2 countries.

Valentina MancioppiDivision of Pediatrics, Department of Health Sciences, University of Piemonte Orientale, Novara, Italy.
Tommaso DaffaraEndocrinology, Department of Translational Medicine, University of Piemonte Orientale, Novara, Italy.
Martina RomanisioEndocrinology, Department of Translational Medicine, University of Piemonte Orientale, Novara, Italy.
Giovanni CeccariniObesity and Lipodystrophy Center, Endocrinology Unit, University Hospital of Pisa, Pisa, Italy.
Caterina PelosiniChemistry and Endocrinology Laboratory, Department of Laboratory Medicine, University Hospital of Pisa, Pisa, Italy.
Ferruccio SantiniObesity and Lipodystrophy Center, Endocrinology Unit, University Hospital of Pisa, Pisa, Italy.
Simonetta BelloneDivision of Pediatrics, Department of Health Sciences, University of Piemonte Orientale, Novara, Italy.
Simona MelloneLaboratory of Genetics, Struttura Complessa a Direzione Universitaria (SCDU) Biochimica Clinica, Ospedale Maggiore della Carità, Novara, Italy.
Alessio BaricichPhysical Medicine and Rehabilitation, Department of Health Sciences, University of Piemonte Orientale, Novara, Italy.
Ivana RabboneDivision of Pediatrics, Department of Health Sciences, University of Piemonte Orientale, Novara, Italy.
Gianluca AimarettiEndocrinology, Department of Translational Medicine, University of Piemonte Orientale, Novara, Italy.
Baris AkinciDivision of Endocrinology and Metabolism, Faculty of Medicine, Dokuz Eylul University, Izmir, Türkiye.
Mara GiordanoLaboratory of Genetics, Struttura Complessa a Direzione Universitaria (SCDU) Biochimica Clinica, Ospedale Maggiore della Carità, Novara, Italy.
Flavia ProdamDivision of Pediatrics, Department of Health Sciences, University of Piemonte Orientale, Novara, Italy.
Università degli Studi del Piemonte Orientale “Amedeo Avogadro” · ITAzienda Ospedaliera Universitaria Pisana · ITDokuz Eylül University · TRFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico · ITOspedale Maggiore · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lipodystrophy syndromes are characterized by a progressive metabolic impairment secondary to adipose tissue dysfunction and may have a genetic background. Congenital generalized lipodystrophy type 4 (CGL4) is an extremely rare subtype, caused by mutations in the polymerase I and transcript release factor (

Indexed as

LipodystrophyLipodystrophy, Congenital GeneralizedMuscular DiseasesChild, PreschoolHumansMutationSiblingsadipose tissueCGL4leptinlipodystrophymuscular dystrophyPTRF

Identifiers

PMID37501786
PMCPMC10369054
OpenAlexW4384008614

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.