Evidence map›Paper›PMID 37503061›Full record

ArticlebioRxiv : the preprint server for biology2023

A paradigm for ethanol consumption in head-fixed mice during prefrontal cortical two-photon calcium imaging.

Anagha Kalelkar, Grayson Sipe, Ana Raquel Castro E Costa, Ilka M Lorenzo, My Nguyen, Ivan Linares-Garcia, Elena Vazey, Rafiq Huda

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Anagha KalelkarWM Keck Center for Collaborative Neuroscience, Department of Cell Biology and Neuroscience, Rutgers University - New Brunswick, 604 Allison Road, Piscataway NJ, 08904, USA.
Grayson SipeDepartment of Brain and Cognitive Science, Picower Institute for Learning and Memory, Massachusetts Institute of Technology, 43 Vassar Street, Cambridge MA, 02139, USA.
Ana Raquel Castro E CostaWM Keck Center for Collaborative Neuroscience, Department of Cell Biology and Neuroscience, Rutgers University - New Brunswick, 604 Allison Road, Piscataway NJ, 08904, USA.
Ilka M LorenzoWM Keck Center for Collaborative Neuroscience, Department of Cell Biology and Neuroscience, Rutgers University - New Brunswick, 604 Allison Road, Piscataway NJ, 08904, USA.
My NguyenWM Keck Center for Collaborative Neuroscience, Department of Cell Biology and Neuroscience, Rutgers University - New Brunswick, 604 Allison Road, Piscataway NJ, 08904, USA.
Ivan Linares-GarciaWM Keck Center for Collaborative Neuroscience, Department of Cell Biology and Neuroscience, Rutgers University - New Brunswick, 604 Allison Road, Piscataway NJ, 08904, USA.
Elena VazeyDepartment of Biology, The University of Massachusetts Amherst, 611 North Pleasant Street, Amherst MA, 01003, USA.
Rafiq HudaWM Keck Center for Collaborative Neuroscience, Department of Cell Biology and Neuroscience, Rutgers University - New Brunswick, 604 Allison Road, Piscataway NJ, 08904, USA.
Rutgers, The State University of New Jersey · USMcGovern Institute for Brain Research · USUniversity of Massachusetts Amherst · US

Funding

4/8: INIA Stress and Chronic Alcohol Interactions: Impact of stress mediated locus coeruleus dysregulation on cognitive control and excessive drinkingU01AA025481 · NIAAA · UNIVERSITY OF MASSACHUSETTS AMHERST · PI DAVID E MOORMAN, Elena Vazey · 2017 to 2026
$4.2M
Prefrontal circuits for attention and motor planningR00MH112855 · NIMH · RUTGERS, THE STATE UNIV OF N.J. · PI HUDA, RAFIQ · 2020 to 2022
$742k
Arousal-induced noradrenergic signaling modulates cortical astrocyte-neuron circuits during ethanol consumptionK99AA028579 · NIAAA · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI SIPE, GRAYSON OREN · 2021 to 2022
$370k
NIAAA NIH HHS K99 AA028579NIAAA NIH HHS U01 AA025481NIMH NIH HHS R00 MH112855
6 · The paper itself

Abstract

The prefrontal cortex (PFC) is a hub for higher-level cognitive behaviors and is a key target for neuroadaptations in alcohol use disorders. Preclinical models of ethanol consumption are instrumental for understanding how acute and repeated drinking affects PFC structure and function. Recent advances in genetically encoded sensors of neuronal activity and neuromodulator release combined with functional microscopy (multiphoton and one-photon widefield imaging) allow multimodal

Indexed as

Alcoholanterior cingulate cortexbinge drinkingcalcium imagingethanolhead-fixedprefrontal cortextwo-photon

Identifiers

PMID37503061
PMCPMC10370124
OpenAlexW4385141972

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.