Evidence map›Paper›PMID 37504885›Full record

ArticleJournal of functional biomaterials2023

Magnesium-Rich Calcium Phosphate Derived from Tilapia Bone Has Superior Osteogenic Potential.

Xiaxin Cao, Jiaqi Zhu, Changze Zhang, Jiaru Xian, Mengting Li, Swastina Nath Varma, Ziyu Qin, Qiaoyuan Deng, Xinyue Zhang, Wei Yang and 1 more

Abstract read
In one paragraph

Article in Journal of functional biomaterials, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Xiaxin CaoHainan Provincial Fine Chemical Engineering Research Center, Hainan University, Haikou 570228, China.
Jiaqi ZhuHainan Provincial Fine Chemical Engineering Research Center, Hainan University, Haikou 570228, China.
Changze ZhangHainan Provincial Fine Chemical Engineering Research Center, Hainan University, Haikou 570228, China.
Jiaru XianHainan Provincial Fine Chemical Engineering Research Center, Hainan University, Haikou 570228, China.
Mengting LiHainan Provincial Fine Chemical Engineering Research Center, Hainan University, Haikou 570228, China.ORCID 0000-0001-6867-1052
Swastina Nath VarmaInstitute of Orthopaedic & Musculoskeletal Science, University College London, Royal National Orthopaedic Hospital, London HA7 4LP, UK.ORCID 0000-0002-9449-8772
Ziyu QinHainan Provincial Fine Chemical Engineering Research Center, Hainan University, Haikou 570228, China.
Qiaoyuan DengKey Laboratory of Advanced Material of Tropical Island Resources of Educational Ministry School of Materials Science and Engineering, Hainan University, Haikou 570228, China.
Xinyue ZhangHainan Provincial Fine Chemical Engineering Research Center, Hainan University, Haikou 570228, China.
Wei YangHainan Provincial Fine Chemical Engineering Research Center, Hainan University, Haikou 570228, China.
Chaozong LiuHainan Provincial Fine Chemical Engineering Research Center, Hainan University, Haikou 570228, China.ORCID 0000-0002-9854-4043

Funding

Engineering and Physical Sciences Research Council via DTP CASE Program EP/T517793/1MRC-UCL Therapeutic Acceleration Support (TAS) Fund 564022Natural Science Foundation of Hainan Province GHYF2022001NIHR UCLH BRC-UCL Therapeutic Acceleration Support (TAS) Fund 564021
6 · The paper itself

Abstract

We extracted magnesium-rich calcium phosphate bioceramics from tilapia bone using a gradient thermal treatment approach and investigated their chemical and physicochemical properties. X-ray diffraction showed that tilapia fish bone-derived hydroxyapatite (FHA) was generated through the first stage of thermal processing at 600-800 °C. Using FHA as a precursor, fish bone biphasic calcium phosphate (FBCP) was produced after the second stage of thermal processing at 900-1200 °C. The beta-tricalcium phosphate content in the FBCP increased with an increasing calcination temperature. The fact that the lattice spacing of the FHA and FBCP was smaller than that of commercial hydroxyapatite (CHA) suggests that Mg-substituted calcium phosphate was produced via the gradient thermal treatment. Both the FHA and FBCP contained considerable quantities of magnesium, with the FHA having a higher concentration. In addition, the FHA and FBCP, particularly the FBCP, degraded faster than the CHA. After one day of degradation, both the FHA and FBCP released Mg

Indexed as

calcium phosphate bioceramicsgradient thermal sinteringosteogenesistilapia bone

Identifiers

PMID37504885
PMCPMC10381238

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.