Evidence map›Paper›PMID 37504910›Full record

Trial reportMarine drugs2023

Oral Supplementation with Algal Sulphated Polysaccharide in Subjects with Inflammatory Skin Conditions: A Randomised Double-Blind Placebo-Controlled Trial and Baseline Dietary Differences.

Lauren A Roach, Barbara J Meyer, J Helen Fitton, Pia Winberg

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Marine drugs, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 13 citations in OpenAlex.

  1. Effect of anNutrients · 2026
    Trial
  2. Trial
  3. Review
  4. Review
  5. Review
  6. Review
  7. Review
  8. Review
  9. Antioxidants (Basel, Switzerland) · 2024
    Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Lauren A RoachSchool of Medical, Indigenous and Health Sciences, Molecular Horizons, Illawarra Health and Medical Research Institute, University of Wollongong, Wollongong, NSW 2522, Australia.ORCID 0000-0002-5353-7405
Barbara J MeyerSchool of Medical, Indigenous and Health Sciences, Molecular Horizons, Illawarra Health and Medical Research Institute, University of Wollongong, Wollongong, NSW 2522, Australia.ORCID 0000-0001-7962-7890
J Helen FittonRDadvisor, Hobart, TAS 7006, Australia.ORCID 0000-0002-1402-0809
Pia WinbergVenus Shell Systems Pty Ltd., Nowra, NSW 2540, Australia.ORCID 0000-0003-2554-4955
University of Wollongong · AU

Funding

Faculty of Science Medicine and Health (SMAH) Research Partnership Grant, University of Wollongong, NSW Australia entitled Gut, skin and metabolic health study of seaweed dietary fibres - BioBelly Study 2, 2017 2017University of Wollongong 2017
6 · The paper itself

Abstract

We examined the effect of a dietary seaweed extract-sulfated xylorhamnoglucuronan (SXRG84)-on individuals with inflammatory skin conditions. A subgroup analysis of a larger trial was undertaken, where 44 participants with skin conditions were enrolled in a double-blind placebo-controlled crossover design. Subjects ingested either SXRG84 extract (2 g/day) for six weeks and placebo for six weeks, or vice versa. At baseline, six- and twelve-weeks inflammatory markers and the gut microbiota were assessed, as well as skin assessments using the dermatology quality of life index (DQLI), psoriasis area severity index (PASI) and visual analogue scales (VAS). There were significant differences at weeks six and twelve for pro-inflammatory cytokines IFN-γ (

Indexed as

PsoriasisQuality of LifeCytokinesDietary SupplementsDouble-Blind MethodHumansTreatment OutcomeTumor Necrosis Factor-alphaCytokinesTumor Necrosis Factor-alphaanti-inflammatoryatopyPalmoplantar Keratodermapsoriasisseaweedskinsulfated polysaccharideSXRG84

Identifiers

PMID37504910
PMCPMC10381427
OpenAlexW4382403215

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.