Evidence map›Paper›PMID 37507632›Full record

ArticleJournal of clinical immunology2023

Atypical Localization of Eczema Discriminates DOCK8 or STAT3 Deficiencies from Atopic Dermatitis.

Nurhan Kasap, Altan Kara, Velat Celik, Sevgi Bilgic Eltan, Idil Akay Haci, Hulya Kose, Ayse Aygun, Emre Akkelle, Nalan Yakici, Sukru Nail Guner and 12 more

Open access · greenAbstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Journal of clinical immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Italian pediatric experts' consensus statement on diagnosis and management of primary atopic disorders.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2025
    Guideline
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 10 institutions in 4 countries.

Nurhan KasapDivision of Pediatric Allergy/Immunology, Faculty of Medicine, Pediatric Allergy and Immunology, Marmara University, Fevzi Çakmak Mah. No: 41, Pendik, Istanbul, Turkey.
Altan KaraTUBITAK Marmara Research Center, Gene Engineering and Biotechnology Institute, Gebze, Turkey.
Velat CelikFaculty of Medicine, Pediatric Allergy and Immunology, Trakya University, Edirne, Turkey.
Sevgi Bilgic EltanDivision of Pediatric Allergy/Immunology, Faculty of Medicine, Pediatric Allergy and Immunology, Marmara University, Fevzi Çakmak Mah. No: 41, Pendik, Istanbul, Turkey.
Idil Akay HaciDepartment of Pediatric Allergy and Immunology, Dr Behçet Uz Children's Hospital, Izmir, Turkey.
Hulya KoseDepartment of Pediatric Immunology and Rheumatology, Medical Faculty, Uludag University, Bursa, Turkey.
Ayse AygunDepartment of Pediatrics, Division of Immunology, Faculty of Medicine, Ege University, Izmir, Turkey.
Emre AkkellePediatric Allergy and Immunology Department, Sancaktepe Training and Research Hospital, Istanbul, Turkey.
Nalan YakiciPediatric Allergy and Immunology Department, Faculty of Medicine, Karadeniz Teknik University, Trabzon, Turkey.
Sukru Nail GunerDivision of Pediatric Allergy and Immunology, Meram Medical Faculty, Necmettin Erbakan University, Konya, Turkey.
Ismail ReisliDivision of Pediatric Allergy and Immunology, Meram Medical Faculty, Necmettin Erbakan University, Konya, Turkey.
Sevgi KelesDivision of Pediatric Allergy and Immunology, Meram Medical Faculty, Necmettin Erbakan University, Konya, Turkey.
Sukru CekicDepartment of Pediatric Immunology and Rheumatology, Medical Faculty, Uludag University, Bursa, Turkey.
Sara Sebnem KilicDepartment of Pediatric Immunology and Rheumatology, Medical Faculty, Uludag University, Bursa, Turkey.
Neslihan Edeer KaracaDepartment of Pediatrics, Division of Immunology, Faculty of Medicine, Ege University, Izmir, Turkey.
Nesrin GulezDepartment of Pediatric Allergy and Immunology, Dr Behçet Uz Children's Hospital, Izmir, Turkey.
Ferah GenelDepartment of Pediatric Allergy and Immunology, Dr Behçet Uz Children's Hospital, Izmir, Turkey.
Ahmet OzenDivision of Pediatric Allergy/Immunology, Faculty of Medicine, Pediatric Allergy and Immunology, Marmara University, Fevzi Çakmak Mah. No: 41, Pendik, Istanbul, Turkey.
Ayse Deniz YuceltenDepartment of Dermatology, Faculty of Medicine, Marmara University, Istanbul, Turkey.
Elif Karakoc-AydinerDivision of Pediatric Allergy/Immunology, Faculty of Medicine, Pediatric Allergy and Immunology, Marmara University, Fevzi Çakmak Mah. No: 41, Pendik, Istanbul, Turkey.
Klaus Schmitz-AbeDivision of Immunology, Boston Children's Hospital, Boston, MA, USA.
Safa BarisDivision of Pediatric Allergy/Immunology, Faculty of Medicine, Pediatric Allergy and Immunology, Marmara University, Fevzi Çakmak Mah. No: 41, Pendik, Istanbul, Turkey. safabaris@hotmail.com.ORCID 0000-0002-4730-9422
Marmara University · TRBursa Uludağ Üni̇versi̇tesi̇ · TRDr. Behçet Uz Çocuk Hastalıkları Hastanesi · TRNecmettin Erbakan University · TREge University · TRBoston Children's Hospital · USCenter for Translational Molecular Medicine · NLKaradeniz Technical University · TRTrakya University · TRTÜBİTAK Marmara Research Center · TR

Funding

The Scientific and Technological Research Council of Turkey 318S202
6 · The paper itself

Abstract

purposeAutosomal recessive dedicator of cytokinesis 8 (DOCK8

methodsThis multicenter study involved 100 patients with DOCK8

resultsThere were 43 patients with DOCK8

conclusionsThe described features can be easily implemented by physicians providing early diagnosis of DOCK8 and STAT3 deficiencies.

Indexed as

Dermatitis, AtopicEczemaJob SyndromePneumoniaCD8-Positive T-LymphocytesGuanine Nucleotide Exchange FactorsHumansInfant, NewbornSTAT3 Transcription FactorDOCK8 protein, humanGuanine Nucleotide Exchange FactorsSTAT3 protein, humanSTAT3 Transcription FactorAtopic dermatitisDOCK8 deficiencyEczema localizationsSTAT3 deficiency

Identifiers

PMID37507632
OpenAlexW4385332241

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.