Evidence map›Paper›PMID 37508580›Full record

ArticleCells2023

MicroRNA-Based Discovery of Biomarkers, Therapeutic Targets, and Repositioning Drugs for Breast Cancer.

Qing Ye, Rebecca A Raese, Dajie Luo, Juan Feng, Wenjun Xin, Chunlin Dong, Yong Qian, Nancy Lan Guo

Open access · goldAbstract read
In one paragraph

Article in Cells, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. miRNA-Based Technologies in Cancer Therapy.Journal of personalized medicine · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Qing YeWest Virginia University Cancer Institute/Mary Babb Randolph Cancer Center, West Virginia University, Morgantown, WV 26506, USA.ORCID 0000-0002-1054-8796
Rebecca A RaeseWest Virginia University Cancer Institute/Mary Babb Randolph Cancer Center, West Virginia University, Morgantown, WV 26506, USA.
Dajie LuoWest Virginia University Cancer Institute/Mary Babb Randolph Cancer Center, West Virginia University, Morgantown, WV 26506, USA.
Juan FengWest Virginia University Cancer Institute/Mary Babb Randolph Cancer Center, West Virginia University, Morgantown, WV 26506, USA.
Wenjun XinWest Virginia University Cancer Institute/Mary Babb Randolph Cancer Center, West Virginia University, Morgantown, WV 26506, USA.
Chunlin DongWest Virginia University Cancer Institute/Mary Babb Randolph Cancer Center, West Virginia University, Morgantown, WV 26506, USA.
Yong QianHealth Effects Laboratory Division, National Institute for Occupational and Safety & Health, Morgantown, WV 26505, USA.
Nancy Lan GuoWest Virginia University Cancer Institute/Mary Babb Randolph Cancer Center, West Virginia University, Morgantown, WV 26506, USA.ORCID 0000-0002-8050-6268
West Virginia University · USNational Institute for Occupational Safety and Health · US

Funding

THE ROLE OF HEF1 PROTEIN IN INVASION OF METASTATIC BREAST CANCERP20RR016440 · NCRR · WEST VIRGINIA UNIVERSITY · PI GIBSON, LAURA F. · 2001 to 2010
$22.8M
Southeast Xlerator NetworkUT2GM130174 · NIGMS · XLERATEHEALTH, LLC · PI KRENTSEL, EUGENE, MCCLURE, IAN D · 2018 to 2020
$3.7M
A Novel Computational Framework for Individualized Clinical Decision-MakingR01LM009500 · NLM · WEST VIRGINIA UNIVERSITY · PI GUO, NANCY LAN · 2008 to 2010
$987k
A Novel Computational Framework for individualized clinical decision-makingR56LM009500 · NLM · WEST VIRGINIA UNIVERSITY · PI GUO, NANCY LAN · 2012 to 2013
$499k
NCRR NIH HHS P20 RR016440NIGMS NIH HHS UT2 GM130174NIH HHS NIGMS/XLerateHealth LLC (4UT2GM130174) I2P AwardNIH HHS P20RR16440 & ARRA SupplementNIH HHS R01/R56LM009500NLM NIH HHS R56 LM009500
6 · The paper itself

Abstract

Breast cancer treatment can be improved with biomarkers for early detection and individualized therapy. A set of 86 microRNAs (miRNAs) were identified to separate breast cancer tumors from normal breast tissues (

Indexed as

Breast NeoplasmsMammary Neoplasms, AnimalMicroRNAsAnimalsArtificial IntelligenceBiomarkersDrug RepositioningFemaleHumansBiomarkersMicroRNAsartificial intelligencebreast cancer diagnosisCRISPR-Cas9/RNAidrug discoverydrug responsemicroRNArepositioning drugs

Identifiers

PMID37508580
PMCPMC10378316
OpenAlexW4385161739

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.