Evidence map›Paper›PMID 37509355›Full record

ReviewCancers2023

Intraoperative Imaging in Hepatopancreatobiliary Surgery.

Tereza Husarova, William M MacCuaig, Isabel S Dennahy, Emma J Sanderson, Barish H Edil, Ajay Jain, Morgan M Bonds, Molly W McNally, Katerina Menclova, Jiri Pudil and 5 more

Abstract readReview
In one paragraph

Review in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Assessment of Breast Tumors Using Multispectral Optoacoustic Tomography in a Surgical Setting.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2025
    Trial
  2. Article
  3. Observational
  4. Using a novel three-dimensional holographic technology to perform open vascular surgery procedures.Journal of vascular surgery cases and innovative techniques · 2024
    Article
  5. Theranostic nanoparticles for detection and treatment of pancreatic cancer.Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Tereza HusarovaDepartment of Surgery, University of Oklahoma Health Science Center, Oklahoma City, OK 73104, USA.ORCID 0000-0001-7672-2286
William M MacCuaigDepartment of Surgery, University of Oklahoma Health Science Center, Oklahoma City, OK 73104, USA.
Isabel S DennahyDepartment of Surgery, University of Oklahoma Health Science Center, Oklahoma City, OK 73104, USA.
Emma J SandersonDepartment of Surgery, University of Oklahoma Health Science Center, Oklahoma City, OK 73104, USA.
Barish H EdilDepartment of Surgery, University of Oklahoma Health Science Center, Oklahoma City, OK 73104, USA.
Ajay JainDepartment of Surgery, University of Oklahoma Health Science Center, Oklahoma City, OK 73104, USA.
Morgan M BondsDepartment of Surgery, University of Oklahoma Health Science Center, Oklahoma City, OK 73104, USA.
Molly W McNallyDepartment of Surgery, University of Oklahoma Health Science Center, Oklahoma City, OK 73104, USA.
Katerina MenclovaDepartment of Surgery, Military University Hospital Prague, 16902 Prague, Czech Republic.
Jiri PudilDepartment of Surgery, Military University Hospital Prague, 16902 Prague, Czech Republic.
Pavel ZarubaDepartment of Surgery, Military University Hospital Prague, 16902 Prague, Czech Republic.
Radek PohnanDepartment of Surgery, Military University Hospital Prague, 16902 Prague, Czech Republic.
Christina E HensonDepartment of Radiation Oncology, University of Oklahoma Health Science Center, Oklahoma City, OK 73104, USA.ORCID 0000-0002-5419-4125
William E GrizzleDepartment of Pathology, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Lacey R McNallyDepartment of Surgery, University of Oklahoma Health Science Center, Oklahoma City, OK 73104, USA.

Funding

Tissue Pathology Shared ResourceP30CA225520 · NCI · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI ROBERT S. MANNEL · 2018 to 2026
$27.1M
Non-Invasive Detection of Tumor Extracellular pH using Multispectral Optoacoustic TomographyR01CA205941 · NCI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI MCNALLY, LACEY R · 2016 to 2021
$1.7M
Development of an apoptosis biosensor for monitoring of breast cancerR01EB034731 · NIBIB · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI HENARY, MAGED M, MCNALLY, LACEY R · 2023 to 2025
$1.5M
Tumor-Specific Nanocontrast Agents for Improved Detection of Pancreatic CancerF31CA261044 · NCI · UNIVERSITY OF OKLAHOMA · PI MACCUAIG, WILLIAM · 2022 to 2023
$79k
NCI NIH HHS f31ca261044NCI NIH HHS F31 CA261044NCI NIH HHS p30ca225520NCI NIH HHS P30 CA225520NCI NIH HHS R01 CA205941NCI NIH HHS R01CA205941NCI NIH HHS R01EB034731NCI NIH HHS U54CA118949NIBIB NIH HHS R01 EB034731
6 · The paper itself

Abstract

Hepatopancreatobiliary surgery belongs to one of the most complex fields of general surgery. An intricate and vital anatomy is accompanied by difficult distinctions of tumors from fibrosis and inflammation; the identification of precise tumor margins; or small, even disappearing, lesions on currently available imaging. The routine implementation of ultrasound use shifted the possibilities in the operating room, yet more precision is necessary to achieve negative resection margins. Modalities utilizing fluorescent-compatible dyes have proven their role in hepatopancreatobiliary surgery, although this is not yet a routine practice, as there are many limitations. Modalities, such as photoacoustic imaging or 3D holograms, are emerging but are mostly limited to preclinical settings. There is a need to identify and develop an ideal contrast agent capable of differentiating between malignant and benign tissue and to report on the prognostic benefits of implemented intraoperative imaging in order to navigate clinical translation. This review focuses on existing and developing imaging modalities for intraoperative use, tailored to the needs of hepatopancreatobiliary cancers. We will also cover the application of these imaging techniques to theranostics to achieve combined diagnostic and therapeutic potential.

Indexed as

hepatopancreatobiliary surgeryimage-guided surgeryintraoperative imagingtargeted imaging

Identifiers

PMID37509355
PMCPMC10377919

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.