Evidence map›Paper›PMID 37509461›Full record

ArticleBiomedicines2023

Lipoprotein(a) As a Potential Predictive Factor for Earlier Aortic Valve Replacement in Patients with Bicuspid Aortic Valve.

Aleksandra Krzesińska, Maria Nowak, Agnieszka Mickiewicz, Gabriela Chyła-Danił, Agnieszka Ćwiklińska, Olga M Koper-Lenkiewicz, Joanna Kamińska, Joanna Matowicka-Karna, Marcin Gruchała, Maciej Jankowski and 2 more

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Aleksandra KrzesińskaDepartment of Clinical Chemistry, Medical University of Gdańsk, 80-211 Gdańsk, Poland.ORCID 0000-0002-4413-0128
Maria Nowak1st Department of Cardiology, Medical University of Gdańsk, 80-211 Gdańsk, Poland.
Agnieszka Mickiewicz1st Department of Cardiology, Medical University of Gdańsk, 80-211 Gdańsk, Poland.ORCID 0000-0003-1707-3807
Gabriela Chyła-DaniłDepartment of Clinical Chemistry, Medical University of Gdańsk, 80-211 Gdańsk, Poland.
Agnieszka ĆwiklińskaDepartment of Clinical Chemistry, Medical University of Gdańsk, 80-211 Gdańsk, Poland.ORCID 0000-0003-1426-3744
Olga M Koper-LenkiewiczDepartment of Clinical Laboratory Diagnostics, Medical University of Białystok, 15-269 Białystok, Poland.ORCID 0000-0001-5199-2773
Joanna KamińskaDepartment of Clinical Laboratory Diagnostics, Medical University of Białystok, 15-269 Białystok, Poland.ORCID 0000-0002-2986-4852
Joanna Matowicka-KarnaDepartment of Clinical Laboratory Diagnostics, Medical University of Białystok, 15-269 Białystok, Poland.
Marcin Gruchała1st Department of Cardiology, Medical University of Gdańsk, 80-211 Gdańsk, Poland.
Maciej JankowskiDepartment of Clinical Chemistry, Medical University of Gdańsk, 80-211 Gdańsk, Poland.ORCID 0000-0003-4540-6955
Marcin Fijałkowski1st Department of Cardiology, Medical University of Gdańsk, 80-211 Gdańsk, Poland.ORCID 0000-0002-2913-5457
Agnieszka KuchtaDepartment of Clinical Chemistry, Medical University of Gdańsk, 80-211 Gdańsk, Poland.ORCID 0000-0003-2264-1442
Gdańsk Medical University · PLMedical University of Białystok · PL

Funding

Gdańsk Medical University 01-0520/08/524(01-50022)Gdańsk Medical University ST 01-50023/0004938National Centre for Research and Development POWR.03.05.00-00-z082/18
6 · The paper itself

Abstract

Bicuspid aortic valve (BAV) affects 0.5-2% of the general population and constitutes the major cause of severe aortic valve stenosis (AVS) in individuals ≤70 years. The aim of the present study was to evaluate the parameters that may provide information about the risk of AVS developing in BAV patients, with particular emphasis on lipoprotein(a) (Lp(a)), which is a well-recognized risk factor for stenosis in the general population. We also analyzed the impact of autotaxin (ATX) and interleukin-6 (IL-6) as parameters potentially related to the pathomechanism of Lp(a) action. We found that high Lp(a) levels (>50 mg/dL) occurred significantly more frequently in patients with AVS than in patients without AVS, both in the group below and above 45 years of age (

Indexed as

aortic valve stenosisautotaxinAVSBAVbicuspid aortic valvecardiovascular diseaselipid profile parameterslipoprotein(a)Lp(a)

Identifiers

PMID37509461
PMCPMC10376971
OpenAlexW4382060621

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.