Evidence map›Paper›PMID 37510190›Full record

ArticleDiagnostics (Basel, Switzerland)2023

The Impact of the COVID-19 Pandemic on Outcomes in Acute Pancreatitis: A Propensity Score Matched Study Comparing before and during the Pandemic.

Patricia Mihaela Rădulescu, Elena Irina Căluianu, Emil Tiberius Traşcă, Dorin Mercuţ, Ion Georgescu, Eugen Florin Georgescu, Eleonora Daniela Ciupeanu-Călugăru, Maria Filoftea Mercuţ, Răzvan Mercuţ, Vlad Padureanu and 3 more

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 8 citations in OpenAlex.

  1. Observational
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Observational
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Patricia Mihaela RădulescuUMF Craiova Doctoral School, University of Pharmacy and Medicine Craiova, 200349 Craiova, Romania.
Elena Irina CăluianuGeneral Surgery Department, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
Emil Tiberius TraşcăGeneral Surgery Department, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
Dorin MercuţGeneral Surgery Department, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
Ion GeorgescuGeneral Surgery Department, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
Eugen Florin GeorgescuGeneral Surgery Department, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
Eleonora Daniela Ciupeanu-CălugăruDepartment of Biology and Environmental Engineering, University of Craiova, 200585 Craiova, Romania.
Maria Filoftea MercuţDepartment of Ophthalmology, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
Răzvan MercuţDepartment of Plastic and Reconstructive Surgery, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
Vlad PadureanuInternal Medicine Department, Country Hospital of Craiova, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.ORCID 0000-0001-7398-5689
Costin Teodor StrebaDepartment of Pneumology, University of Pharmacy and Medicine Craiova, 200349 Craiova, Romania.
Cristina CălăraşuDepartment of Pneumology, University of Pharmacy and Medicine Craiova, 200349 Craiova, Romania.
Dumitru RădulescuGeneral Surgery Department, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.ORCID 0009-0003-3990-6483
University of Medicine and Pharmacy of Craiova · ROUniversity of Craiova · RO

Funding

S.C. TOP DIABET S.R.L., Craiova, Romania, Research Grant of the University of Medicine and Pharmacy of Craiova 26/727/4/27.07.2022
6 · The paper itself

Abstract

We aimed to evaluate the outcomes and survival of patients with acute pancreatitis who shared the same clinical form, age, and sex before the pandemic, during the pandemic, and among those with confirmed COVID-19 infection upon hospital admission. This consideration used the sparse data in the existing literature on the influence of the pandemic and COVID-19 infection on patients with acute pancreatitis. To accomplish this, we conducted a multicentric, retrospective case-control study using propensity score matching with a 2:1 match of 28 patients with SARS-CoV-2 infection and acute pancreatitis, with 56 patients with acute pancreatitis pre-pandemic, and 56 patients with acute pancreatitis during the pandemic. The study outcome demonstrated a six-fold relative risk of death in patients with acute pancreatitis and SARS-CoV-2 infection compared to those with acute pancreatitis before the pandemic. Furthermore, restrictive measures implemented during the pandemic period led to a partial delay in the care of patients with acute pancreatitis, which likely resulted in an impairment of their immune state. This, in certain circumstances, resulted in a restriction of surgical treatment indications, leading to a three-fold relative risk of death in patients with acute pancreatitis during the pandemic compared to those with acute pancreatitis before the pandemic.

Indexed as

acute pancreatitisaverage crepuscular volume–lymphocyte ratioCOVID-19cumulative inflammatory indexIICMCVLneutrophil–lymphocyte ratioNLRpandemic

Identifiers

PMID37510190
PMCPMC10378087
OpenAlexW4385218196

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.