Evidence map›Paper›PMID 37511333›Full record

ArticleInternational journal of molecular sciences2023

The Arduous Path to Drug Approval for the Management of Prader-Willi Syndrome: A Historical Perspective and Call to Action.

Deepan Singh, Jennifer L Miller, Edward Robert Wassman, Merlin G Butler, Allison Foley Shenk, Monica Converse, Maria Picone

Abstract readEditorial
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Deepan SinghDepartment of Psychiatry, Maimonides Medical Center, Brooklyn, New York, NY 11219, USA.
Jennifer L MillerDepartment of Pediatrics, Division of Pediatric Endocrinology, University of Florida, Gainesville, FL 32611, USA.
Edward Robert WassmanTREND Community, Philadelphia, PA 19103, USA.ORCID 0000-0003-0293-7676
Merlin G ButlerDepartments of Psychiatry & Behavioral Sciences and Pediatrics, University of Kansas Medical Center, Kansas City, KS 66160, USA.ORCID 0000-0002-2911-0524
Allison Foley ShenkTREND Community, Philadelphia, PA 19103, USA.
Monica ConverseTREND Community, Philadelphia, PA 19103, USA.ORCID 0000-0002-1856-0650
Maria PiconeTREND Community, Philadelphia, PA 19103, USA.ORCID 0000-0002-6802-8363

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prader-Willi syndrome (PWS) is a neuroendocrine genetic disorder resulting from the loss of paternally expressed imprinted genes in chromosome 15q11-q13 [...].

Indexed as

Prader-Willi SyndromeChromosomesChromosomes, Human, Pair 15Drug ApprovalGenomic ImprintingHumans

Identifiers

PMID37511333
PMCPMC10381011

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.