Evidence map›Paper›PMID 37511344›Full record

ArticleInternational journal of molecular sciences2023

High CD142 Level Marks Tumor-Promoting Fibroblasts with Targeting Potential in Colorectal Cancer.

András Áron Soós, Andrea Kelemen, Adrián Orosz, Zsuzsanna Szvicsek, Tamás Tölgyes, Kristóf Dede, Attila Bursics, Zoltán Wiener

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

András Áron SoósDepartment of Genetics, Cell and Immunobiology, Semmelweis University, H-1089 Budapest, Hungary.
Andrea KelemenDepartment of Genetics, Cell and Immunobiology, Semmelweis University, H-1089 Budapest, Hungary.
Adrián OroszDepartment of Genetics, Cell and Immunobiology, Semmelweis University, H-1089 Budapest, Hungary.
Zsuzsanna SzvicsekDepartment of Genetics, Cell and Immunobiology, Semmelweis University, H-1089 Budapest, Hungary.
Tamás TölgyesUzsoki Teaching Hospital, H-1145 Budapest, Hungary.
Kristóf DedeUzsoki Teaching Hospital, H-1145 Budapest, Hungary.
Attila BursicsUzsoki Teaching Hospital, H-1145 Budapest, Hungary.
Zoltán WienerDepartment of Genetics, Cell and Immunobiology, Semmelweis University, H-1089 Budapest, Hungary.ORCID 0000-0001-7056-4926
Semmelweis University · HUUzsoki Hospital · HU

Funding

Hungarian Academy of Sciences BO/00131/20/8Hungarian Scientific Research Fund 137554Ministry of Innovation and Technology of Hungary TKP2021-EGA-24ÚNKP New National Excellence Program, Ministry of Innovation and Technology of Hungary ÚNKP-21-5-SE-16
6 · The paper itself

Abstract

Colorectal cancer (CRC) has a high incidence and is one of the leading causes of cancer-related death. The accumulation of cancer-associated fibroblasts (CAF) induces an aggressive, stem-like phenotype in tumor cells, and it indicates a poor prognosis. However, cellular heterogeneity among CAFs and the targeting of both stromal and CRC cells are not yet well resolved. Here, we identified CD142

Indexed as

Cancer-Associated FibroblastsColorectal NeoplasmsCell Line, TumorCell ProliferationFibroblastsHumansNeoplasm Recurrence, LocalThromboplastinTumor MicroenvironmentThromboplastinBCL familyCAFcancer-associated fibroblastcolorectal cancerdrug sensitivityF3hepatocyte growth factorheterogeneityHGFHSP90inhibitorJQ1MEKorganoidtissue factor

Identifiers

PMID37511344
PMCPMC10381019
OpenAlexW4384826081

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.