Evidence map›Paper›PMID 37511370›Full record

ArticleInternational journal of molecular sciences2023

Cx43 Hemichannel and Panx1 Channel Modulation by Gap19 and

Alessio Lissoni, Siyu Tao, Rosalie Allewaert, Katja Witschas, Luc Leybaert

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Hemichannels contribute to mitochondrial CaFrontiers in cell and developmental biology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Alessio LissoniDepartment of Basic and Applied Medical Sciences-Physiology Group, Ghent University, 9000 Ghent, Belgium.ORCID 0000-0002-5931-3576
Siyu TaoDepartment of Basic and Applied Medical Sciences-Physiology Group, Ghent University, 9000 Ghent, Belgium.ORCID 0000-0003-3858-1093
Rosalie AllewaertDepartment of Basic and Applied Medical Sciences-Physiology Group, Ghent University, 9000 Ghent, Belgium.
Katja WitschasDepartment of Basic and Applied Medical Sciences-Physiology Group, Ghent University, 9000 Ghent, Belgium.ORCID 0000-0002-0960-683X
Luc LeybaertDepartment of Basic and Applied Medical Sciences-Physiology Group, Ghent University, 9000 Ghent, Belgium.ORCID 0000-0001-6452-6982
Ghent University · BE

Funding

Research Foundation - Flanders G040720NResearch Foundation - Flanders G052718NResearch Foundation - Flanders G063023N
6 · The paper itself

Abstract

Cx43 hemichannels (HCs) and Panx1 channels are two genetically distant protein families. Despite the lack of sequence homology, Cx43 and Panx1 channels have been the subject of debate due to their overlapping expression and the fact that both channels present similarities in terms of their membrane topology and electrical properties. Using the mimetic peptides Gap19 and

Indexed as

Connexin 43Gap JunctionsConnexinsHeLa CellsHumansNerve Tissue ProteinsPeptidesConnexin 43ConnexinsGJA1 protein, humanNerve Tissue ProteinsPANX1 protein, humanPeptideschannel gatingCx43Panx1single-channel analysis

Identifiers

PMID37511370
PMCPMC10380488
OpenAlexW4384827596

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.