Evidence map›Paper›PMID 37511434›Full record

ArticleInternational journal of molecular sciences2023

Perinatal S-Adenosylmethionine Supplementation Represses

Tiziana Raia, Federica Armeli, Rosaria A Cavallaro, Giampiero Ferraguti, Rita Businaro, Marco Lucarelli, Andrea Fuso

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Tiziana RaiaDepartment of Experimental Medicine, Sapienza University of Rome, 00161 Rome, Italy.ORCID 0000-0002-6449-5554
Federica ArmeliDepartment of Medico-Surgical Sciences and Biotechnologies, Sapienza University of Rome, 04100 Latina, Italy.ORCID 0000-0002-4981-3374
Rosaria A CavallaroDepartment of Surgery, Sapienza University of Rome, 00161 Rome, Italy.
Giampiero FerragutiDepartment of Experimental Medicine, Sapienza University of Rome, 00161 Rome, Italy.ORCID 0000-0001-6129-4071
Rita BusinaroDepartment of Medico-Surgical Sciences and Biotechnologies, Sapienza University of Rome, 04100 Latina, Italy.ORCID 0000-0002-7890-8524
Marco LucarelliDepartment of Experimental Medicine, Sapienza University of Rome, 00161 Rome, Italy.ORCID 0000-0002-5538-2494
Andrea FusoDepartment of Experimental Medicine, Sapienza University of Rome, 00161 Rome, Italy.ORCID 0000-0001-9467-5671
Sapienza University of Rome · ITIstituto Pasteur · IT

Funding

European Commission 278486Gnosis by Lesaffre n/a
6 · The paper itself

Abstract

DNA methylation, the main epigenetic modification regulating gene expression, plays a role in the pathophysiology of neurodegeneration. Previous evidence indicates that 5'-flanking hypomethylation of

Indexed as

Alzheimer DiseaseS-AdenosylmethionineAnimalsDietary SupplementsDNA MethylationEpigenetic MemoryFemaleMiceMice, TransgenicPregnancyS-AdenosylmethionineAlzheimer’s diseaseDNA methylationMIPs (non-CpG methylation-insensitive primers)neurodegenerationnon-CpG methylationperinatal treatmentpresenilin 1

Identifiers

PMID37511434
PMCPMC10380323
OpenAlexW4384829414

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.