Evidence map›Paper›PMID 37511465›Full record

ArticleInternational journal of molecular sciences2023

Metabolic, Apoptotic and Fibro-Inflammatory Profiles of the Heart Exposed to Environmental Electromagnetic Fields.

Lesia Savchenko, Ilenia Martinelli, Dimitri Marsal, Oksana Batkivska, Vyacheslav Zhdan, Igor Kaidashev, Nathalie Pizzinat, Frederic Boal, Helene Tronchere, Junwu Tao and 1 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Lesia SavchenkoNational Institute of Health and Medical Research (INSERM) U1297, CEDEX 4, 31432 Toulouse, France.
Ilenia MartinelliNational Institute of Health and Medical Research (INSERM) U1297, CEDEX 4, 31432 Toulouse, France.ORCID 0000-0002-7702-7784
Dimitri MarsalNational Institute of Health and Medical Research (INSERM) U1297, CEDEX 4, 31432 Toulouse, France.ORCID 0000-0001-5518-5514
Oksana BatkivskaNational Institute of Health and Medical Research (INSERM) U1297, CEDEX 4, 31432 Toulouse, France.ORCID 0000-0001-6724-2651
Vyacheslav ZhdanPoltava State Medical University, 23 Shevchenko, 36000 Poltava, Ukraine.
Igor KaidashevPoltava State Medical University, 23 Shevchenko, 36000 Poltava, Ukraine.
Nathalie PizzinatNational Institute of Health and Medical Research (INSERM) U1297, CEDEX 4, 31432 Toulouse, France.
Frederic BoalNational Institute of Health and Medical Research (INSERM) U1297, CEDEX 4, 31432 Toulouse, France.ORCID 0000-0001-7607-4573
Helene TronchereNational Institute of Health and Medical Research (INSERM) U1297, CEDEX 4, 31432 Toulouse, France.ORCID 0000-0001-6117-8054
Junwu TaoUniversity Toulouse III, 118 Route de Narbonne, CEDEX 9, 31062 Toulouse, France.
Oksana KunduzovaNational Institute of Health and Medical Research (INSERM) U1297, CEDEX 4, 31432 Toulouse, France.

Funding

French Agency for Food, Environmental and Occupational Health & Safety EST-2016 RF-01
6 · The paper itself

Abstract

Environmental stress can disturb the integrative functioning of the cardiovascular system and trigger a number of adaptive and/or maladaptive cell responses. Concomitant with the expanding use of mobile communication systems, public exposure to electromagnetic fields (EMFs) raises the question of the impact of 900 MHz EMFs on cardiovascular health. Therefore, in this study, we experimentally investigated whether 915 MHz EMF exposure influenced cardiac metabolic, antioxidant, apoptotic, and fibro-inflammatory profiles in a mouse model. Healthy mice were sham-exposed or exposed to EMF for 14 days. Western blot analysis using whole cardiac tissue lysates demonstrated that there was no significant change in the expression of oxidative phosphorylation (OXPHOS) complexes between the control and EMF-exposed mice. In addition, the myocardial expression of fibro-inflammatory cytokines, antioxidant enzymes, and apoptosis-related markers remained unchanged in the EMF-challenged hearts. Finally, the structural integrity of the cardiac tissues was preserved among the groups. These findings suggest that the apoptotic, antioxidant, metabolic, and fibro-inflammatory profiles of the heart remained stable under conditions of EMF exposure in the analyzed mice.

Indexed as

Electromagnetic FieldsFibromyalgiaAnimalsAntioxidantsHeartMiceMyocardiumOxidative StressAntioxidantsantioxidantsapoptosiselectromagnetic stressorfibrosisinflammation

Identifiers

PMID37511465
PMCPMC10380359

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.