Evidence map›Paper›PMID 37511745›Full record

ReviewJournal of personalized medicine2023

Personalized Medicine in Medullary Thyroid Carcinoma: A Broad Review of Emerging Treatments.

Rui Sousa Martins, Tito Teles Jesus, Luís Cardoso, Paula Soares, João Vinagre

Open access · goldAbstract readReview
In one paragraph

Review in Journal of personalized medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Clinical Outcomes of the GermlineMedicina (Kaunas, Lithuania) · 2026
    Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Rui Sousa MartinsInstituto de Investigação e Inovação em Saúde (i3S), Universidade do Porto, 4200-135 Porto, Portugal.ORCID 0000-0003-1349-3281
Tito Teles JesusInstituto de Investigação e Inovação em Saúde (i3S), Universidade do Porto, 4200-135 Porto, Portugal.
Luís CardosoInstituto de Investigação e Inovação em Saúde (i3S), Universidade do Porto, 4200-135 Porto, Portugal.ORCID 0000-0001-9833-7960
Paula SoaresInstituto de Investigação e Inovação em Saúde (i3S), Universidade do Porto, 4200-135 Porto, Portugal.ORCID 0000-0001-9607-6998
João VinagreInstituto de Investigação e Inovação em Saúde (i3S), Universidade do Porto, 4200-135 Porto, Portugal.ORCID 0000-0002-0871-1427
Universidade do Porto · PT

Funding

European Regional Development Fund (ERDF) NORTE-01-0145-FEDER-000051Fundação para a Ciência e Tecnologia 2022.00276.CEECIND; 2021.05640.BD; PTDC/MED-ONC/0531/2021; UID/BIM/04293/2019;PORTO.CCC - Porto.Comprehensive Cancer Center Raquel Seruca NORTE-01-0145-FEDER-072678Sociedade Portuguesa de Endocrinologia, Diabetes e Metabolismo RET-altered medullary thyroid cancer: what are we missing?
6 · The paper itself

Abstract

Medullary thyroid carcinoma (MTC) arises from parafollicular cells in the thyroid gland, and although rare, it represents an aggressive type of thyroid cancer. MTC is recognized for its low mutational burden, with point mutations in

Indexed as

MTCmultikinase inhibitorsRETRET-specific inhibitorssignaling pathwaysTKIs

Identifiers

PMID37511745
PMCPMC10381735
OpenAlexW4384340713

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.