Evidence map›Paper›PMID 37511756›Full record

ArticleJournal of personalized medicine2023

Effects of Vasopressin Receptor Agonists during the Resuscitation of Hemorrhagic Shock: A Systematic Review and Meta-Analysis of Experimental and Clinical Studies.

Eleni Laou, Nikolaos Papagiannakis, Androniki Papadopoulou, Theodora Choratta, Minas Sakellakis, Mariachiara Ippolito, Ioannis Pantazopoulos, Andrea Cortegiani, Athanasios Chalkias

Open access · goldAbstract read
In one paragraph

Article in Journal of personalized medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Trial
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 7 institutions in 3 countries.

Eleni LaouDepartment of Anesthesiology, Agia Sophia Children's Hospital, 15773 Athens, Greece.
Nikolaos PapagiannakisFirst Department of Neurology, Eginition University Hospital, Medical School, National and Kapodistrian University of Athens, 11528 Athens, Greece.ORCID 0000-0002-8401-8472
Androniki PapadopoulouDepartment of Anesthesiology, G. Gennimatas General Hospital, 54635 Thessaloniki, Greece.
Theodora ChorattaDepartment of General Surgery, Metaxa Hospital, 18537 Piraeus, Greece.ORCID 0009-0004-9234-0439
Minas SakellakisDepartment of Medical Oncology, Metropolitan Hospital, 18547 Piraeus, Greece.
Mariachiara IppolitoDepartment of Surgical, Oncological and Oral Science (Di.Chir.On.S.), University of Palermo, 90133 Palermo, Italy.ORCID 0000-0001-9851-6301
Ioannis PantazopoulosDepartment of Emergency Medicine, Faculty of Medicine, University of Thessaly, 41500 Larisa, Greece.ORCID 0000-0002-8846-519X
Andrea CortegianiDepartment of Surgical, Oncological and Oral Science (Di.Chir.On.S.), University of Palermo, 90133 Palermo, Italy.ORCID 0000-0003-1416-9993
Athanasios ChalkiasDepartment of Anesthesiology, Faculty of Medicine, University of Thessaly, 41500 Larisa, Greece.ORCID 0000-0002-7634-4665
University of Palermo · ITUniversity of Thessaly · GRChildren's Hospital Agia Sophia · GRGeneral Hospital of Athens G. Genimatas · GRMetaxa Hospital · GRMetropolitan Hospital · GRNational and Kapodistrian University of Athens · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe clinical impact of vasopressin in hemorrhagic shock remains largely unknown.

objectiveThis systematic review and meta-analysis was designed to investigate the effects of vasopressin receptor agonists during the resuscitation of hemorrhagic shock.

methodsA systematic search of PubMed (MEDLINE), Scopus, and PubMed Central was conducted for relevant articles. Experimental (animal) and clinical studies were included. The primary objective was to investigate the correlation of vasopressin receptor agonist use with mortality and various hemodynamic parameters.

resultsData extraction was possible in thirteen animal studies and two clinical studies. Differences in risk of mortality between patients who received a vasopressin receptor agonist were not statistically significant when compared to those who were not treated with such agents [RR (95% CI): 1.17 (0.67, 2.08);

conclusionsDifferences in risk of mortality between patients who received a vasopressin receptor agonist were not statistically significant when compared to those who were not treated with such agents after hemorrhagic shock. More data are needed to deduce certain conclusions.

Indexed as

hemodynamicshemorrhagic shockoutcomeresuscitationvasopressinvasopressin receptor agonist

Identifiers

PMID37511756
PMCPMC10381354
OpenAlexW4384557819

What Socratic holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.