ReviewLife (Basel, Switzerland)2023
What Is the Best Treatment of the Femoral Shaft Nonunion after Intramedullary Nailing? A Systematic Review.
Review in Life (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 11 citations in OpenAlex.
- What is the rate and degree of deformity in femoral diaphyseal nonunion? A CT-based retrospective cohort study.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2026Article
- Effect of postoperative fracture gap on bone union in femoral diaphyseal fractures treated with intramedullary nailing: a retrospective clinical study.Journal of orthopaedic surgery and research · 2026Article
- Article
- Retaining intramedullary nail with plate fixation outperforms nail removal and double-plate fixation in femoral shaft nonunion.European journal of medical research · 2026Article
- Peri-implant femoral fractures in elderly: Morbidity, mortality, treatment options and good practices.Chinese journal of traumatology = Zhonghua chuang shang za zhi · 2025Article
- The Effects and Mechanisms of Low-Intensity Pulsed Ultrasound on Bone Remodeling: From Laboratory to Clinic.Biomolecules · 2025Review
- Article
- Combined monolateral external fixation and intramedullary nailing for oligotrophic femoral nonunion with limb length discrepancy: a case series of technical strategy and surgical outcomes.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2025Article
- Radial extracorporeal shock wave promotes the treatment of non-union of femoral shaft fractures in children: a case report.Frontiers in surgery · 2025Article
- Comparative Study of Exchange Nailing and Augmentative Plating for Treating Aseptic Nonunion of Femoral Shafts Post Intramedullary Nailing: A Single-Blind, Multicentric Randomized Clinical Trial.Journal of clinical medicine · 2024Article
- Neglected Ipsilateral Non-Union Neck of Femur with Shaft of Femur Non-Union in A Young Patient and Its Management - A Rare Case Report.Journal of orthopaedic case reports · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Nonunion (NU) is one of the most feared complications of femoral shaft fracture treatment. Femoral shaft fracture treatment is often linked with poor bone stock and reduced bone metabolism. In this paper, the goal is to carefully analyze the best treatment options for patients who developed nonunion after the intramedullary nailing of a femoral shaft fracture. A systematic review of the literature available in the PubMed, EMBASE and Cochran library databases was carried out, and 16 studies were included. Exclusion criteria included case reports and case series that do not have data about clinical outcomes or functional outcomes and included fewer than 10 patients. The reviewed data provide evidence for very good results about the treatment of this pathology with exchanging intramedullary nails or the implantation of a plate and screws (general healing rate of 96.3%). Moreover, the data support the utilization of autologous bone graft in order to stimulate the healing process. In conclusion, the choice between these two types of treatment must be guided by the type of pseudarthrosis that the patient presents. Additionally, bone grafting or growth factors promote bone regenerative processes, especially in patients with oligo-atrophic pseudoarthrosis.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.