Evidence map›Paper›PMID 37512322›Full record

ArticleMaterials (Basel, Switzerland)2023

Electrostatic and Covalent Binding of an Antibacterial Polymer to Hydroxyapatite for Protection against

Sudip Chakraborty, Georgio Katsifis, Iman Roohani, Cyrille Boyer, David McKenzie, Mark D P Willcox, Renxun Chen, Naresh Kumar

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Materials (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sudip ChakrabortySchool of Chemistry, UNSW Sydney, Sydney, NSW 2052, Australia.
Georgio KatsifisSchool of Physics, University of Sydney, Sydney, NSW 2006, Australia.
Iman RoohaniSchool of Chemistry, UNSW Sydney, Sydney, NSW 2052, Australia.
Cyrille BoyerSchool of Chemical Engineering, UNSW Sydney, Sydney, NSW 2052, Australia.
David McKenzieSchool of Physics, University of Sydney, Sydney, NSW 2006, Australia.
Mark D P WillcoxSchool of Optometry and Vision Science, UNSW Sydney, Sydney, NSW 2052, Australia.ORCID 0000-0003-3842-7563
Renxun ChenSchool of Chemistry, UNSW Sydney, Sydney, NSW 2052, Australia.ORCID 0000-0003-0828-9980
Naresh KumarSchool of Chemistry, UNSW Sydney, Sydney, NSW 2052, Australia.ORCID 0000-0002-0951-9621

Funding

National Health and Medical Research Council APP1183597
6 · The paper itself

Abstract

Orthopedic-device-related infections are notorious for causing physical and psychological trauma to patients suffering from them. Traditional methods of treating these infections have relied heavily on antibiotics and are becoming ineffectual due to the rise of antibiotic-resistant bacteria. Mimics of antimicrobial peptides have emerged as exciting alternatives due to their favorable antibacterial properties and lack of propensity for generating resistant bacteria. In this study, the efficacy of an antibacterial polymer as a coating material for hydroxyapatite and glass surfaces, two materials with wide ranging application in orthopedics and the biomedical sciences, is demonstrated. Both physical and covalent modes of attachment of the polymer to these materials were explored. Polymer attachment to the material surfaces was confirmed via X-ray photoelectron spectroscopy and contact angle measurements. The modified surfaces exhibited significant antibacterial activity against the Gram-negative bacterium

Indexed as

antimicrobial coatingsantimicrobial peptidesantimicrobial polymersbiomaterialshydroxyapatite

Identifiers

PMID37512322
PMCPMC10385198

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.