Evidence map›Paper›PMID 37512568›Full record

ArticleMetabolites2023

Ultraviolet Radiation-Induced Mitochondrial Disturbances Are Attenuated by Metabolites of Melatonin in Human Epidermal Keratinocytes.

Chantal E Holtkamp, Dawid Warmus, Klaudia Bonowicz, Maciej Gagat, Kinga Linowiecka, Agnieszka Wolnicka-Glubisz, Russel J Reiter, Markus Böhm, Andrzej T Slominski, Kerstin Steinbrink and 1 more

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Metabolites, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Evolutionary formation of melatonin and vitamin D in early life forms: insects take centre stage.Biological reviews of the Cambridge Philosophical Society · 2024
    Review
  8. Melatonin/Sericin Wound Healing Patches: Implications for Melanoma Therapy.International journal of molecular sciences · 2024
    Review
  9. Review
  10. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 3 countries.

Chantal E HoltkampDepartment of Dermatology, University of Münster, Von-Esmarch-Str. 58, 48149 Münster, Germany.
Dawid WarmusDepartment of Biophysics and Cancer Biology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Gronostajowa 7, 30-387 Krakow, Poland.ORCID 0000-0002-1332-4130
Klaudia BonowiczDepartment of Histology and Embryology, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, 85-092 Bydgoszcz, Poland.ORCID 0000-0002-2098-2799
Maciej GagatDepartment of Histology and Embryology, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, 85-092 Bydgoszcz, Poland.ORCID 0000-0002-5445-8821
Kinga LinowieckaDepartment of Human Biology, Faculty of Biological and Veterinary Sciences, Nicolaus Copernicus University, Lwowska 1, 87-100 Toruń, Poland.ORCID 0000-0002-7029-2657
Agnieszka Wolnicka-GlubiszDepartment of Biophysics and Cancer Biology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Gronostajowa 7, 30-387 Krakow, Poland.ORCID 0000-0003-3070-6349
Russel J ReiterDepartment of Cell Systems and Anatomy, UT Health, Long School of Medicine, San Antonio, TX 78229, USA.ORCID 0000-0001-6763-4225
Markus BöhmDepartment of Dermatology, University of Münster, Von-Esmarch-Str. 58, 48149 Münster, Germany.
Andrzej T SlominskiDepartment of Dermatology, Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, AL 35294, USA.ORCID 0000-0001-8963-3995
Kerstin SteinbrinkDepartment of Dermatology, University of Münster, Von-Esmarch-Str. 58, 48149 Münster, Germany.ORCID 0000-0002-0500-2158
Konrad KleszczyńskiDepartment of Dermatology, University of Münster, Von-Esmarch-Str. 58, 48149 Münster, Germany.ORCID 0000-0002-1311-263X
University of Münster · DEJagiellonian University · PLNicolaus Copernicus University · PLThe University of Texas Health Science Center at San Antonio · USUniversity of Alabama at Birmingham · USUniversity of Miami · US

Funding

Mechanism of action and function of novel secosteroid 20(OH)D3 in the skinR01AR073004 · NIAMS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI ANDRZEJ T SLOMINSKI · 2018 to 2026
$2.9M
Significance of metabolic activation of lumisterol in the skinR01AR071189 · NIAMS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI SLOMINSKI, ANDRZEJ T · 2017 to 2021
$1.6M
CYP11A1-derived secosteroids as therapeutic agents in UVB induced skin cancerI01BX004293 · VA · BIRMINGHAM VA MEDICAL CENTER · PI SLOMINSKI, ANDRZEJ T · 2019 to 2025
–
BLRD VA I01 BX004293NIAMS NIH HHS R01 AR071189NIAMS NIH HHS R01 AR073004NIH HHS 1R01AR073004-01A1NIH HHS R01AR071189-01A1
6 · The paper itself

Abstract

Melatonin (

Indexed as

apoptosiscaspaseshuman epidermal keratinocytesindolic metaboliteskynurenic metabolitesmelatoninmitochondriaoxidative stressultraviolet radiation

Identifiers

PMID37512568
PMCPMC10383625
OpenAlexW4384931558

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.