ArticleMolecules (Basel, Switzerland)2023
Quercetin Antagonizes the Sedative Effects of Linalool, Possibly through the GABAergic Interaction Pathway.
Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 35 citations in OpenAlex.
- L-Quebrachitol Enhances Sedative Effect of Diazepam Through GABAergic Pathway: Animal and Computational Studies.Brain and behavior · 2026Article
- Multitarget Neuropharmacological Actions of Drimycarpus racemosus Hook. f. GC-MS-Guided In Vivo and In Silico Evidence of Anxiolytic and Antidepressant Potential.TheScientificWorldJournal · 2026Article
- Sedative potential of palmatine chloride in thiopental sodium-induced chicks: evidence from in vivo and in Silico studies.Scientific reports · 2025Article
- Evaluation of the Sedative Activity of Naringenin: In Vivo Study with Pharmacokinetics and Molecular Docking Insights.ChemistryOpen · 2025Article
- Thymol as a Potential Natural Antiemetic: Insights From In Vivo and In Silico Studies.Food science & nutrition · 2025Article
- Extraction Methods and Sedative-Hypnotic Effects of Total Flavonoids fromPharmaceuticals (Basel, Switzerland) · 2025Article
- Daidzin Enhances the Anticonvulsion Effects of Carbamazepine and Diazepam, Possibly Through Voltage-Gated Sodium Channels and GABAMolecular neurobiology · 2025Article
- Memory-Enhancing Effects of Dauricine in Swiss Mice: Possible Molecular Interventions Through In Vivo and In Silico Studies.Neuromolecular medicine · 2025Article
- Citronellal Exerts Sedative-Like Effects and Augments Diazepam's Action in Swiss Mice, Possibly Through the GABAergic Pathway.Brain and behavior · 2025Article
- Anxiolytic Efficacy of Indirubin: In Vivo Approach Along with Receptor Binding Profiling and Molecular Interaction with GABAergic Pathways.ChemistryOpen · 2025Article
- Monoterpenoid synergy: a new frontier in biological applications.Naunyn-Schmiedeberg's archives of pharmacology · 2025Review
- GABAergic antidepressant effect of daidzin: in vivo approach with in silico receptor binding affinities.In silico pharmacology · 2025Article
- Sclareol exerts an anti-inflammatory effect, possibly through COXs inhibition pathway:Pharmaceutical science advances · 2024Article
- Anti-inflammatory activity of d-pinitol possibly through inhibiting COX-2 enzyme:Frontiers in chemistry · 2024Article
- Glioblastoma Multiforme miRNA based Comprehensive Study to Validate Phytochemicals for Effective Treatment against Deadly Tumour throughMicroRNA (Shariqah, United Arab Emirates) · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 5 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sedatives promote calmness or sleepiness during surgery or severely stressful events. In addition, depression is a mental health issue that negatively affects emotional well-being. A group of drugs called anti-depressants is used to treat major depressive illnesses. The aim of the present work was to evaluate the effects of quercetin (QUR) and linalool (LIN) on thiopental sodium (TS)-induced sleeping mice and to investigate the combined effects of these compounds using a conventional co-treatment strategy and
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.