Evidence map›Paper›PMID 37513887›Full record

ArticlePharmaceuticals (Basel, Switzerland)2023

Luteolin Protects Pancreatic β Cells against Apoptosis through Regulation of Autophagy and ROS Clearance.

Ming Han, Yuting Lu, Yunhua Tao, Xinwen Zhang, Chengqiu Dai, Bingqian Zhang, Honghong Xu, Jingya Li

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
8.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 27 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Ming HanSchool of Chinese Materia Medica, Nanjing University of Chinese Medicine, Nanjing 210046, China.
Yuting LuState Key Laboratory of Drug Research, The National Center for Drug Screening, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
Yunhua TaoState Key Laboratory of Drug Research, The National Center for Drug Screening, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
Xinwen ZhangState Key Laboratory of Drug Research, The National Center for Drug Screening, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
Chengqiu DaiUniversity of Chinese Academy of Sciences, Beijing 100049, China.
Bingqian ZhangState Key Laboratory of Drug Research, The National Center for Drug Screening, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
Honghong XuState Key Laboratory of Drug Research, The National Center for Drug Screening, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
Jingya LiSchool of Chinese Materia Medica, Nanjing University of Chinese Medicine, Nanjing 210046, China.
National Center for Drug Screening · CNUniversity of Chinese Academy of Sciences · CNShanghai Institute of Materia Medica · CN

Funding

National Natural Science Foundation of China 92057116, 81673493,82200885National Science and Technology Major Project 2018ZX09711002-004/018Shanghai Municipal Science and Technology Committee of Shanghai outstanding academic leaders plan 22XD1400600
6 · The paper itself

Abstract

Diabetes, which is mainly characterized by increased apoptosis and dysfunction of beta (β) cells, is a metabolic disease caused by impairment of pancreatic islet function. Previous studies have demonstrated that death-associated protein kinase-related apoptosis-inducing kinase-2 (

Indexed as

autophagyluteolinreactive oxygen speciestype 2 diabetesβ cell

Identifiers

PMID37513887
PMCPMC10385282
OpenAlexW4383695517

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.