Evidence map›Paper›PMID 37515809›Full record

ArticleEpigenetics2023

Impact of testicular cancer on sperm small non-coding RNA signature: a pilot study.

Charlotte Dupont, Maria G Stathopoulou, Pierre-Julien Illy, Nathalie Sermondade, Rachel Levy, Michele Trabucchi, Marie Prades, Rahaf Haj Hamid, Isabelle Berthaut, Valérie Grandjean

Open access · diamondAbstract read
In one paragraph

Article in Epigenetics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Charlotte DupontSorbonne Université, INSERM, Centre de Recherche St-Antoine, CRSA, Paris, France.
Maria G StathopoulouUniversité Cote d'Azur, Inserm U1065, Nice, France.
Pierre-Julien IllyUniversité Cote d'Azur, Inserm U1065, Nice, France.
Nathalie SermondadeSorbonne Université, INSERM, Centre de Recherche St-Antoine, CRSA, Paris, France.
Rachel LevySorbonne Université, INSERM, Centre de Recherche St-Antoine, CRSA, Paris, France.
Michele TrabucchiUniversité Cote d'Azur, Inserm U1065, Nice, France.
Marie PradesSorbonne Université, INSERM, Centre de Recherche St-Antoine, CRSA, Paris, France.
Rahaf Haj HamidSorbonne Université, INSERM, Centre de Recherche St-Antoine, CRSA, Paris, France.
Isabelle BerthautSorbonne Université, INSERM, Centre de Recherche St-Antoine, CRSA, Paris, France.
Valérie GrandjeanUniversité Cote d'Azur, Inserm U1065, Nice, France.ORCID 0000-0003-1661-7411
Inserm · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Testicular germ cell tumours (TGCTs) are the most common tumours in young adults of European ancestry. The high heritability and the constantly increased incidence, which has doubled over the last 20 years, strongly suggest that both genetic and environmental factors are likely to shape the TGCT susceptibility. While genome-wide association studies have identified loci associated with TGCT susceptibility, the role played by environmental molecular vectors in TGCT susceptibility remains unclear. Evidence shows that sperm non-coding RNAs provide a good vision of the environmental stresses experienced by men. Here, to determine whether TGCT impacts the abundance of specific non-coding RNAs in sperm, small RNA deep sequencing analysis of sperm of 25 men aged between 19 and 42 years, diagnosed with (

Indexed as

Neoplasms, Germ Cell and EmbryonalRNA, Small UntranslatedTesticular NeoplasmsAdultDNA MethylationGenetic Predisposition to DiseaseGenome-Wide Association StudyHumansMalePilot ProjectsSemenSpermatozoaYoung AdultRNA, Small Untranslatedepigeneticssmall non-coding RNAsTesticular germ cell tumours

Identifiers

PMID37515809
PMCPMC10388827
OpenAlexW4385374516

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.