Evidence map›Paper›PMID 37517354›Full record

ReviewCurrent opinion in genetics & development2023

Evolutionary dynamics between transposable elements and their host genomes: mechanisms of suppression and escape.

Matthew A Lawlor, Christopher E Ellison

Open access · hybridAbstract readReview
In one paragraph

Review in Current opinion in genetics & development, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
12.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
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  9. Acytota and the evolution of complexity.European biophysics journal : EBJ · 2025
    Review
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  18. rDNA magnification is a unique feature of germline stem cells.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Matthew A LawlorRutgers University, 604 Allison Rd, Piscataway, NJ 08854, USA.
Christopher E EllisonRutgers University, 604 Allison Rd, Piscataway, NJ 08854, USA. Electronic address: chris.ellison@rutgers.edu.
Rutgers, The State University of New Jersey · US

Funding

Mechanisms and evolutionary consequences of transposon strategies to counteract host silencingR01GM140163 · NIGMS · RUTGERS, THE STATE UNIV OF N.J. · PI ELLISON, CHRISTOPHER EUGENE · 2021 to 2024
$1.5M
NIGMS NIH HHS R01 GM140163
6 · The paper itself

Abstract

Transposable elements (TEs) are ubiquitous among eukaryotic species. Their evolutionary persistence is likely due to a combination of tolerogenic, evasive/antagonistic, and cooperative interactions with their host genomes. Here, we focus on metazoan species and review recent advances related to the harmful effects of TE insertions, including how epigenetic effects and TE-derived RNAs can damage host cells. We discuss new findings related to host pathways that silence TEs, such as the piRNA pathway and the APOBEC3 and Kruppel-associated box zinc finger gene families. Finally, we summarize novel strategies used by TEs to evade host silencing, including the Y chromosome as a permissive niche for TE mobilization and TE counterdefense strategies to block host silencing factors.

Indexed as

DNA Transposable ElementsGene SilencingAnimalsBiological EvolutionEvolution, MolecularRNA, Small InterferingDNA Transposable ElementsRNA, Small Interfering

Identifiers

PMID37517354
PMCPMC10530431
OpenAlexW4385372003

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.