Evidence map›Paper›PMID 37519475›Full record

ReviewBiological psychiatry global open science2023

From Computation to Clinic.

Sarah W Yip, Deanna M Barch, Henry W Chase, Shelly Flagel, Quentin J M Huys, Anna B Konova, Read Montague, Martin Paulus

Abstract readReview
In one paragraph

Review in Biological psychiatry global open science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Bridging minds and policies: supporting early career researchers in translating computational psychiatry research.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024
    Article
  9. Cognitive Control in Schizophrenia: Advances in Computational Approaches.Current directions in psychological science · 2024
    Article
  10. Article
  11. Listening to the Data: Computational Approaches to Addiction and Learning.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023
    Review
  12. Article
  13. Computational models of subjective feelings in psychiatry.Neuroscience and biobehavioral reviews · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sarah W YipDepartment of Psychiatry, Yale School of Medicine, New Haven, Connecticut.
Deanna M BarchDepartments of Psychological & Brain Sciences, Psychiatry, and Radiology, Washington University, St. Louis, Missouri.
Henry W ChaseDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania.
Shelly FlagelDepartment of Psychiatry and Michigan Neuroscience Institute, University of Michigan, Ann Arbor, Michigan.
Quentin J M HuysDivision of Psychiatry and Max Planck UCL Centre for Computational Psychiatry and Ageing Research, Institute of Neurology, University College London, London, United Kingdom.
Anna B KonovaDepartment of Psychiatry and Brain Health Institute, Rutgers University, Piscataway, New Jersey.
Read MontagueFralin Biomedical Research Institute and Department of Physics, Virginia Tech, Blacksburg, Virginia.
Martin PaulusLaureate Institute for Brain Research, Tulsa, Oklahoma.

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Decision Neuroscience of CravingR01DA054201 · NIDA · RUTGERS BIOMEDICAL/HEALTH SCIENCES-RBHS · PI KONOVA, ANNA BORISOVA · 2021 to 2025
$2.8M
Computational psychiatry investigation of the role of unrealistic optimism in opioid use disorder and relapseR01DA053282 · NIDA · RUTGERS BIOMEDICAL/HEALTH SCIENCES-RBHS · PI KONOVA, ANNA BORISOVA · 2021 to 2025
$2.8M
NCATS NIH HHS UL1 TR001863NIDA NIH HHS R01 DA053282NIDA NIH HHS R01 DA054201
6 · The paper itself

Abstract

Theory-driven and data-driven computational approaches to psychiatry have enormous potential for elucidating mechanism of disease and providing translational linkages between basic science findings and the clinic. These approaches have already demonstrated utility in providing clinically relevant understanding, primarily via back translation from clinic to computation, revealing how specific disorders or symptoms map onto specific computational processes. Nonetheless, forward translation, from computation to clinic, remains rare. In addition, consensus regarding specific barriers to forward translation-and on the best strategies to overcome these barriers-is limited. This perspective review brings together expert basic and computationally trained researchers and clinicians to 1) identify challenges specific to preclinical model systems and clinical translation of computational models of cognition and affect, and 2) discuss practical approaches to overcoming these challenges. In doing so, we highlight recent evidence for the ability of computational approaches to predict treatment responses in psychiatric disorders and discuss considerations for maximizing the clinical relevance of such models (e.g., via longitudinal testing) and the likelihood of stakeholder adoption (e.g., via cost-effectiveness analyses).

Indexed as

Cognitive neuroscienceComputational psychiatryMachine learningNeuroimagingReinforcement learning

Identifiers

PMID37519475
PMCPMC10382698

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.