Evidence map›Paper›PMID 37519716›Full record

ArticleHeliyon2023

Gene co-expression network identifies critical genes, pathways and regulatory motifs mediating the progression of rift valley fever in

John K Gitau, Rosaline W Macharia, Kennedy W Mwangi, Nehemiah Ongeso, Edwin Murungi

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Heliyon, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

John K GitauUniversity of Nairobi, Biochemistry Department, P.O Box 30197, 00100, Nairobi, Kenya.
Rosaline W MachariaUniversity of Nairobi, Biochemistry Department, P.O Box 30197, 00100, Nairobi, Kenya.
Kennedy W MwangiJomo Kenyatta University of Agriculture and Technology, P.O Box 62000, 00200, Nairobi, Kenya.
Nehemiah OngesoUniversity of Nairobi, Biochemistry Department, P.O Box 30197, 00100, Nairobi, Kenya.
Edwin MurungiKisii University, Department of Medical Biochemistry, P.O Box 408, 40200, Kisii, Kenya.
University of Nairobi · KEJomo Kenyatta University of Agriculture and Technology · KEKisii University · KE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rift Valley Fever (RVF) is a mosquito-borne viral disease caused by the Rift Valley Fever Virus. The disease is a zoonosis that largely affects domestic animals, including sheep, goats, and cattle, resulting in severe morbidity and mortality marked by massive storm abortions. To halt human and livestock deaths due to RVF, the development of efficacious vaccines and therapeutics is a compelling and urgent priority. We sought to identify potential key modules (gene clusters), hub genes, and regulatory motifs involved in the pathogenesis of RVF in

Indexed as

Bos taurusHub genesInnate immune responseModulesRegulatory motifsRift valley feverweighted gene co-expression network

Identifiers

PMID37519716
PMCPMC10375796
OpenAlexW4384157307

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.