Evidence map›Paper›PMID 37520254›Full record

ArticlePeerJ2023

Utilization of hepatitis B surface antigen-positive donors in liver transplantation for recipients with hepatocellular carcinoma: a retrospective and propensity score matching analysis.

Zhitao Chen, Yihao Ma, Yuqi Dong, Chuanbao Chen, Hanyu Wang, Tielong Wang, Jia Yu, Xitao Hong, Maogen Chen, Xiaoshun He and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PeerJ, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Zhitao Chen *Organ Transplant Center, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Grangdong, People's Republic of China.
Yihao Ma *Organ Transplant Center, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Grangdong, People's Republic of China.
Yuqi DongOrgan Transplant Center, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Grangdong, People's Republic of China.
Chuanbao ChenOrgan Transplant Center, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Grangdong, People's Republic of China.
Hanyu WangOrgan Transplant Center, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Grangdong, People's Republic of China.
Tielong WangOrgan Transplant Center, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Grangdong, People's Republic of China.
Jia YuOrgan Transplant Center, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Grangdong, People's Republic of China.
Xitao HongOrgan Transplant Center, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Grangdong, People's Republic of China.
Maogen ChenOrgan Transplant Center, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Grangdong, People's Republic of China.
Xiaoshun HeOrgan Transplant Center, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Grangdong, People's Republic of China.
Weiqiang JuOrgan Transplant Center, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Grangdong, People's Republic of China.
Key Laboratory of Guangdong Province · CNThe First Affiliated Hospital, Sun Yat-sen University · CNSun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The use of extended criteria donor (ECD) grafts such as donor with infection of hepatitis B virus (HBV) is a potential solution for organ shortage. In this study, we aimed to evaluate the safety and long-term survival of utilization of hepatitis B surface antigen-positive (HBsAg+) donor livers in HCC patients using propensity score matching (PSM) analysis. Methods: Forty-eight donors with HBsAg-positive and 279 donors with HBsAg-negative were transplanted and enrolled in this study. PSM analysis were used to eliminate selection bias. Perioperative data and survival were collected and analyzed. Results: PSM generated 44 patient pairs. When comparing intra- and post-operative data, no significant difference was found between groups ( Conclusion: In conclusion, with adequate antiviral prophylaxis and treatment, utilization of HBsAg positive liver grafts did not increase the incidence of early-stage complications. However, patient with an HBsAg-positive graft had poorer progression-free survival and overall survival.

Indexed as

Carcinoma, HepatocellularHepatitis BHepatitis B Surface AntigensLiver NeoplasmsLiver TransplantationTissue DonorsAdultFemaleHumansMaleMiddle AgedPropensity ScoreRetrospective StudiesRisk FactorsHepatitis B Surface AntigensHepatitis B antigen-positive donorHepatocellular carcinomaLiver transplantationOverall survivalProgression-free survivalPropensity score matching

Identifiers

PMID37520254
PMCPMC10386819
OpenAlexW4385318354

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.