Evidence map›Paper›PMID 37522209›Full record

ArticleJournal of Alzheimer's disease : JAD2023

Cognition and Cognitive Changes in a Low-Income Sub-Saharan African Aging Population.

Iliana V Kohler, Fabrice Kämpfen, Chiwoza Bandawe, Hans-Peter Kohler

Open access · greenAbstract read
In one paragraph

Article in Journal of Alzheimer's disease : JAD, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
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  7. Down syndrome in Africa: Challenges, opportunities, and future directions.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 3 countries.

Iliana V KohlerPopulation Studies Center and Department of Sociology, University of Pennsylvania, Philadelphia, PA, USA.
Fabrice KämpfenSchool of Economics, University College Dublin, Ireland.
Chiwoza BandaweDepartment of Psychiatry and Mental Health, Kamuzu University of Health Sciences (KUHeS), Blantyre, Malawi.
Hans-Peter KohlerPopulation Aging Research Center and Department of Sociology, University of Pennsylvania, Philadelphia, PA, USA.
University of Pennsylvania · USKamuzu Central Hospital · MWUniversity College Dublin · IE

Funding

Virus & Reservoirs CoreP30AI045008 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI Ronald G Collman · 1999 to 2026
$78.6M
STATISTICAL DATA ENCLAVE COREP30AG012836 · NIA · UNIVERSITY OF PENNSYLVANIA · PI COE, NORMA B · 1999 to 2024
$14.0M
Population Science Research Center Development CoreR24HD044964 · NICHD · UNIVERSITY OF PENNSYLVANIA · PI SMITH, HERBERT L. · 2003 to 2017
$9.8M
Sci-Tech Core-Population Dynamics Research CenterP2CHD044964 · NICHD · UNIVERSITY OF PENNSYLVANIA · PI EMILIO ALBERTO PARRADO · 2018 to 2026
$5.3M
Surviving an Epidemic: Families and Well-Being, Malawi 1998-2020R01HD087391 · NICHD · UNIVERSITY OF PENNSYLVANIA · PI ANGLEWICZ, PHILIP ANTHONY, KOHLER, HANS-PETER · 2017 to 2022
$2.9M
Consequences of High Morbidity and Mortality in a Low-Income CountryR01HD053781 · NICHD · UNIVERSITY OF PENNSYLVANIA · PI KOHLER, HANS-PETER · 2007 to 2011
$2.9M
AIDS/HIV RISK, Marriage and Sexual Relations in MalawiR01HD044228 · NICHD · UNIVERSITY OF PENNSYLVANIA · PI KOHLER, HANS-PETER · 2003 to 2006
$1.6M
The Benefits of Knowledge: Mortality Risks, Mental health and Life-Cycle BehaviorsR21AG053763 · NIA · UNIVERSITY OF PENNSYLVANIA · PI DELAVANDE, ADELINE, KOHLER, HANS-PETER · 2016 to 2017
$398k
Incentives, Information and Relations in MalawiR21HD050653 · NICHD · UNIVERSITY OF PENNSYLVANIA · PI KOHLER, HANS-PETER · 2005 to 2006
$349k
Subjective Expectations and Health-Related Behavior R03HD058976 · NICHD · RAND CORPORATION · PI DELAVANDE, ADELINE · 2009 to 2010
$190k
Leveraging Social Networks and Linkage to Care to Foster Healthy Aging in a Low-Income ContextR03AG069817 · NIA · UNIVERSITY OF PENNSYLVANIA · PI KOHLER, ILIANA V · 2020 to 2021
$162k
NIAID NIH HHS P30 AI045008NIA NIH HHS P30 AG012836NIA NIH HHS R03 AG069817NIA NIH HHS R21 AG053763NICHD NIH HHS P2C HD044964NICHD NIH HHS R01 HD044228NICHD NIH HHS R01 HD053781NICHD NIH HHS R01 HD087391NICHD NIH HHS R03 HD058976NICHD NIH HHS R21 HD050653NICHD NIH HHS R24 HD044964
6 · The paper itself

Abstract

backgroundCognition and its age-related changes remain vastly understudied in low-income countries (LICs), despite evidence suggesting that cognitive decline among aging low-income populations is a rapidly increasing disease burden often occurring at younger ages as compared to high-income countries (HICs).

objectiveWe examine patterns of cognition among men and women, 45 + years old, living in rural Malawi. We analyze how key socioeconomic characteristics predict levels of cognition and its changes as individuals get older.

methodsUtilizing the Mature Adults Cohort of the Malawi Longitudinal Study of Families and Health (MLSFH-MAC) collected during 2012-2017, we estimate standard regression models to analyze predictors of the age- and sex-specific levels and longitudinal changes in cognition. Cognition is assessed with a screening instrument that is adapted to this low-literacy context and measures different domains such as language, attention, or executive functioning.

resultsWomen have lower levels of cognition than men, a pattern in stark contrast to findings in HICs. Schooling and socioeconomic status increase the probability of having consistently high performance during the cognitive assessment. Cognitive decline accelerates with age and is detectable already at mid-adult ages (45-55 years). Despite lower levels of cognitive function observed among women, the pace of decline with age is similar for both genders.

conclusionWomen are particularly affected by poor cognition in this context. The study emphasizes the importance of prioritizing cognitive health and research on cognition among older individuals in sub-Saharan Africa LICs, to which relatively little health care resources continue to be allocated.

Indexed as

AgingCognitionAgedExecutive FunctionFemaleHumansLongitudinal StudiesMalePovertyAge- and sex-specific patternsAlzheimer’s diseasecognitiongender differenceslongitudinal changeslow-income countriesSub-Saharan Africa

Identifiers

PMID37522209
PMCPMC10588811
OpenAlexW4385233189

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.