Evidence map›Paper›PMID 37522931›Full record

ArticleEJNMMI physics2023

Quantitative analysis of

Benjamin Serrano, Régis Amblard, Tiffany Beaumont, Florent Hugonnet, Matthieu Dietz, Frédéric Berthier, Nicolas Garnier, Rémy Villeneuve, Valérie Nataf, François Mocquot and 3 more

2 registry-linked trialsOpen access · goldAbstract read
In one paragraph

Article in EJNMMI physics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05049551 completednot on this map

Quantitative Analysis of 99mTc-Pertechnetate Thyroid Uptake With a Large Field CZT Gamma Camera: Feasibility and Comparison Between SPECT/CT and Planar Acquisitions

TypeobservationalSponsorCentre Hospitalier Princesse GraceRan2019 to 2020Enrolled23ConditionsHyperthyroidism
NCT07610460 completednot on this mapstarted 2025, after this paper: background citation

Clinical Evaluation of Thyroid Uptake Quantification With Technetium-99m (99mTc)-Pertechnetate: Comparison Between Gold Standard Planar and Quantitative 3D CZT Single Photon Emission Computed Tomography/Cumputed Tomography (SPECT/CT) Scintigraphy

TypeobservationalSponsorCentre Hospitalier Princesse GraceRan2025 to 2026Enrolled27ConditionsHypo or HyperthyroidismArmsNo Intervention: Observational Cohort
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. 360° CZT-SPECT/CT cameras:EJNMMI physics · 2024
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 2 countries.

Benjamin SerranoMedical Physics Department, Centre Hospitalier Princesse Grace, Monaco, Monaco. bserrano@chpg.mc.ORCID http://orcid.org/0000-0002-2210-9803
Régis AmblardMedical Physics Department, Centre Hospitalier Princesse Grace, Monaco, Monaco.
Tiffany BeaumontLaboratoire d'évaluation de la dose interne, Institut de Radioprotection et de Sûreté Nucléaire, Fontenay-aux-Roses, France.
Florent HugonnetNuclear Medicine Department, Centre Hospitalier Princesse Grace, Monaco, Monaco.
Matthieu DietzNuclear Medicine Department, Hospices Civils de Lyon, Lyon, France.
Frédéric BerthierDepartment of Biostatistics, Centre Hospitalier Princesse Grace, Monaco, Monaco.
Nicolas GarnierMedical Physics Department, Centre Hospitalier Princesse Grace, Monaco, Monaco.
Rémy VilleneuveMedical Physics Department, Centre Hospitalier Princesse Grace, Monaco, Monaco.
Valérie NatafNuclear Medicine Department, Centre Hospitalier Princesse Grace, Monaco, Monaco.
François MocquotNuclear Medicine Department, Centre Hospitalier Princesse Grace, Monaco, Monaco.
Christopher MontemagnoDepartment of Medical Biology, Centre Scientifique de Monaco, Monaco, Monaco.
Marc FaraggiNuclear Medicine Department, Centre Hospitalier Princesse Grace, Monaco, Monaco.
Benoît PaulmierNuclear Medicine Department, Centre Hospitalier Princesse Grace, Monaco, Monaco.
Princess Grace Hospital Centre · MCHospices Civils de Lyon · FRInstitut de Radioprotection et de Sûreté Nucléaire · FRScientific Centre of Monaco · MC

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe main objective of this study was to evaluate the ability of a large field Cadmium Zinc Telluride (CZT) camera to estimate thyroid uptake (TU) on single photon emission computed tomography (SPECT) images with and without attenuation correction (Tomo-AC and Tomo-NoAC) compared with Planar acquisition in a series of 23 consecutive patients. The secondary objective was to determine radiation doses for the tracer administration and for the additional Computed Tomography (CT) scan.

methodsCross-calibration factors were determined using a thyroid phantom, for Planar, Tomo-AC and Tomo-NoAC images. Then Planar and SPECT/CT acquisitions centered on the thyroid were performed on 5 anthropomorphic phantoms with activity ranging from 0.4 to 10 MBq, and 23 patients after administration of 79.2 ± 3.7 MBq of [

resultsCross-calibration factors were 66.2 ± 4.9, 60.7 ± 0.7 and 26.5 ± 0.3 counts/(MBq s), respectively, for Planar, Tomo-AC and Tomo-NoAC images. Theoretical and estimated AThA for Planar, Tomo-AC and Tomo-NoAC images were statistically highly correlated (r < 0.99; P < 10

conclusionAThA estimation using Planar and SPECT/CT acquisitions on a new generation of CZT large-field cameras is feasible. In addition, TU on SPECT/CT was as accurate as conventional planar acquisition, but the CT induced additional thyroid exposure. Trial registration Name of the registry: Thyroid Uptake Quantification on a New Generation of Gamma Camera (QUANTHYC). TRIAL NUMBER: NCT05049551. Registered September 20, 2021-Retrospectively registered, https://clinicaltrials.gov/ct2/show/record/NCT05049551?cntry=MC&draw=2&rank=4 .

Indexed as

Absolute activityCZTPlanarQuantificationSPECT/CTThyroidUptake

Identifiers

PMID37522931
PMCPMC10390438
OpenAlexW4385406462

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.