Evidence map›Paper›PMID 37522947›Full record

ReviewApplied microbiology and biotechnology2023

Woodfordia fruticosa (L.) Kurz: in vitro biotechnological interventions and perspectives.

Mahender Aileni, Mallesham Bulle, Ramesh Naik Malavath, Satyamraj Thurpu, Kiranmayi Bandaram, Bhargavi Balkampeta, Meghana Marri, Vijaya Simha Reddy Singasani, E N Murthy

Abstract readReview
PubMed Publisher
In one paragraph

Review in Applied microbiology and biotechnology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mahender Aileni *Department of Biotechnology, Telangana University, Dichpally, Nizamabad, Telangana, 503322, India. mahenderaileni@telanganauniversity.ac.in.ORCID http://orcid.org/0000-0002-3132-154X
Mallesham Bulle *Agri Biotech Foundation, Agricultural University Campus, Rajendranagar, Hyderabad, 500030, Telangana, India. malleshsjgc@gmail.com.ORCID http://orcid.org/0000-0002-5986-2428
Ramesh Naik MalavathDepartment of Biotechnology, Telangana University, Dichpally, Nizamabad, Telangana, 503322, India.
Satyamraj ThurpuDepartment of Biotechnology, Telangana University, Dichpally, Nizamabad, Telangana, 503322, India.
Kiranmayi BandaramDepartment of Biotechnology, Telangana University, Dichpally, Nizamabad, Telangana, 503322, India.
Bhargavi BalkampetaDepartment of Biotechnology, Telangana University, Dichpally, Nizamabad, Telangana, 503322, India.
Meghana MarriDepartment of Biotechnology, Telangana University, Dichpally, Nizamabad, Telangana, 503322, India.
Vijaya Simha Reddy SingasaniDepartment of Biotechnology, Telangana University, Dichpally, Nizamabad, Telangana, 503322, India.
E N MurthyDepartment of Botany, Satavahana University, Karimnagar, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Woodfordia fruticosa (L.) Kurz is a woody medicinal shrub (Lythraceae) commonly known as the "fire flame bush." W. fruticosa plant parts either alone or whole plant have a long history of recommended use in the Indian medicine systems of Ayurveda, Unani, and Siddha (AUS). This plant is prominently known for its pharmacological properties, viz., antimicrobial, anti-inflammatory, anti-peptic ulcer, hepatoprotective, immunomodulatory, antitumor, cardioprotective, analgesic, and wound healing activities. Its important phyto-constituents, woodfordin C, woodfordin I, oenothein B, and isoschimacoalin-A, exhibit in vitro or in vivo physiological activities beneficial to human health. As the plant is a rich storehouse of phyto-constituents, it is indiscriminately used in its wild habitats. Moreover, due to very poor seed viability and difficult-to-root qualities, it is placed under IUCN list of endangered plant species. For W. fruticosa, biomass production or to its conservation by in vitro regeneration is the best feasible alternative. Till date, only few important in vitro regeneration methods are reported in W. fruticosa. ISSR molecular markers based clonal fidelity and Agrobacterium-mediated transformation has been demonstrated, indicating that W. fruticosa is amenable to genetic manipulation and genome editing studies. This review presents concise summary of updated reports on W. fruticosa phyto-constituents and their biological activities, while a critical appraisal of biotechnological interventions, shortcomings, and factors influencing such potential areas success was presented. The unexplored gaps addressed here are relevant for W. fruticosa scientific innovations yet to come. In this paper, for the first time, we have presented a simple and reproducible protocol for synthetic seed production in W. fruticosa. KEY POINTS: • Critical and updated records on W. fruticosa phytochemistry and its activities • In vitro propagation and elicitation of secondary metabolites in W. fruticosa • Key bottlenecks, in vitro flowering, value addition, and outlook in W. fruticosa.

Indexed as

Anti-Infective AgentsWoodfordiaAnti-Inflammatory AgentsHumansPlant ExtractsWound HealingAnti-Infective AgentsAnti-Inflammatory AgentsPlant ExtractsBiotechnological cutting-edge toolsFire flame bushMetabolic engineeringPharmacological studiesSynthetic seedsWoodfordin

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.