Evidence map›Paper›PMID 37524887›Full record

ArticleJournal of behavioral medicine2024

The three-item patient-reported instrument for retrospective adherence in resource constrained settings: reliability, validity and potential utility.

Seth C Kalichman, Ellen Banas, Bruno Shkembi, Moira Kalichman, Catherine Mathews

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Article in Journal of behavioral medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
–field-weighted citation impact, top 87% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Seth C KalichmanInstitute for Collaboration on Health, Intervention, and Policy, University of Connecticut, 406 Babbidge Road, Storrs, CT, 06269, USA. seth.k@uconn.edu.ORCID 0000-0002-0912-5112
Ellen BanasInstitute for Collaboration on Health, Intervention, and Policy, University of Connecticut, 406 Babbidge Road, Storrs, CT, 06269, USA.
Bruno ShkembiInstitute for Collaboration on Health, Intervention, and Policy, University of Connecticut, 406 Babbidge Road, Storrs, CT, 06269, USA.
Moira KalichmanInstitute for Collaboration on Health, Intervention, and Policy, University of Connecticut, 406 Babbidge Road, Storrs, CT, 06269, USA.
Catherine MathewsHealth Systems Research Unit, South African Medical Research Council, Cape Town, South Africa.
University of Connecticut · USSouth African Medical Research Council · ZA

Funding

NIMH NIH HHS R01MH19913
6 · The paper itself

Abstract

introductionPatient-report instruments remain the most feasible and sustainable approaches for monitoring medication adherence in clinical settings. However, questions of their reliability and validity persist. Studies suggest that the 3-item instrument for retrospective adherence (IRA) developed by Wilson et al. offers a viable option for clinically monitoring medication adherence. Here we report the reliability and validity of the IRA among patients recruited from community-based HIV clinics and antiretroviral therapy (ART) dispensaries in a resource constrained township in Cape Town, South Africa.

methodsWomen (n = 794) and men (n = 228) receiving ART completed the IRA at three time points: (a) in a face-to-face administration at enrollment (b) in1-week phone interview and (c) 1-month phone interview. Participants also provided contemporaneous blood samples for HIV viral load testing as a clinical outcome and unannounced phone-based pill counts as an objective assessment of ART adherence.

resultsThe IRA was internally consistent and showed evidence of time stability. The IRA also demonstrated validity with respect to pill count adherence, correlates of adherence, and HIV viral load. Response operating curve analysis yielded an area under the curve of 0.646, using 75% adherence as the cut-off, with 0.637 sensitivity and 0.567 specificity.

conclusionsThe IRA demonstrated reliability, construct validity and criterion validity in a resource constrained setting, supporting use of the IRA in research and clinical care.

Indexed as

Anti-HIV AgentsHIV InfectionsFemaleHumansMaleMedication AdherencePatient Reported Outcome MeasuresReproducibility of ResultsRetrospective StudiesSouth AfricaViral LoadAnti-HIV AgentsClinical monitoringHIV suppressionMedication adherencePatient-reported adherenceSelf-report adherence

Identifiers

PMID37524887
OpenAlexW4385415493

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.