Evidence mapPaperPMID 37525495Full record

ReviewKorean circulation journal2023

The Gut-Heart Axis: Updated Review for The Roles of Microbiome in Cardiovascular Health.

Thi Van Anh Bui, Hyesoo Hwangbo, Yimin Lai, Seok Beom Hong, Yeon-Jik Choi, Hun-Jun Park, Kiwon Ban

Open access · hybridAbstract readReview
In one paragraph

Review in Korean circulation journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
8.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 53 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Review
  9. Article
  10. Review
  11. Review
  12. Who will be our adult congenital heart disease patient tomorrow?European heart journal supplements : journal of the European Society of Cardiology · 2026
    Article
  13. Review
  14. Review
  15. Correlation Between Dysbiosis and Atrial Fibrillation: What's New?International journal of molecular sciences · 2025
    Review
  16. Gut microbiome dysbiosis in heart failure: Updated evidence, mechanisms, and therapeutic directions.American heart journal plus : cardiology research and practice · 2025
    Review
  17. Article
  18. Understanding the intricate interactions between microbiota and host.World journal of experimental medicine · 2025
    Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 4 countries.

Thi Van Anh Bui *Department of Biomedical Sciences, College of Veterinary Medicine and Life Sciences, City University of Hong Kong, Hong Kong SAR.ORCID https://orcid.org/0000-0002-4423-5990
Hyesoo Hwangbo *Department of Biomedical Sciences, College of Veterinary Medicine and Life Sciences, City University of Hong Kong, Hong Kong SAR.ORCID https://orcid.org/0009-0007-3052-5042
Yimin LaiDepartment of Biomedical Sciences, College of Veterinary Medicine and Life Sciences, City University of Hong Kong, Hong Kong SAR.ORCID https://orcid.org/0000-0002-2747-6119
Seok Beom HongDepartment of Thoracic and Cardiovascular Surgery, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.ORCID https://orcid.org/0009-0008-4603-7438
Yeon-Jik ChoiDivision of Cardiology, Department of Internal Medicine, Eunpyeong St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.ORCID https://orcid.org/0000-0003-0720-1449
Hun-Jun ParkDepartment of Biomedicine & Health Sciences, College of Medicine, The Catholic University of Korea, Seoul, Korea.ORCID https://orcid.org/0000-0001-8009-9546
Kiwon BanDepartment of Biomedical Sciences, College of Veterinary Medicine and Life Sciences, City University of Hong Kong, Hong Kong SAR.ORCID https://orcid.org/0000-0003-0805-5439
City University of Hong Kong · HKThe Catholic University of Korea Seoul St. Mary's Hospital · KRSt. Mary's Hospital · US

Funding

CityU Applied Research GrantHong Kong Research Grants Council 21100818Ministry of Health and Welfare 21A0104L1-11Ministry of Science and ICT, South KoreaTFBC project fund
6 · The paper itself

Abstract

Cardiovascular diseases (CVDs), including coronary artery disease, stroke, heart failure, and hypertension, are the global leading causes of death, accounting for more than 30% of deaths worldwide. Although the risk factors of CVDs have been well understood and various treatment and preventive measures have been established, the mortality rate and the financial burden of CVDs are expected to grow exponentially over time due to the changes in lifestyles and increasing life expectancies of the present generation. Recent advancements in metagenomics and metabolomics analysis have identified gut microbiome and its associated metabolites as potential risk factors for CVDs, suggesting the possibility of developing more effective novel therapeutic strategies against CVD. In addition, increasing evidence has demonstrated the alterations in the ratio of

Indexed as

Cardiovascular diseasesMicrobial-dependent metabolitesMicrobiomeShort-chain fatty acidTrimethylamine N-oxide

Identifiers

PMID37525495
PMCPMC10435824
OpenAlexW4384660958

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.