Evidence map›Paper›PMID 37525591›Full record

ArticleBJPsych open2023

Modelling the cost-effectiveness of brief aftercare interventions following hospital-treated self-harm.

Long Khanh-Dao Le, Anna Flego, Karolina Krysinska, Karl Andriessen, Piumee Bandara, Andrew Page, Marisa Schlichthorst, Jane Pirkis, Cathrine Mihalopoulos, Greg Carter and 1 more

Open access · goldAbstract read
In one paragraph

Article in BJPsych open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact, top 86% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 0 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Long Khanh-Dao LeHealth Economics Division, School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.ORCID https://orcid.org/0000-0002-9442-6824
Anna FlegoCentre for Mental Health, Melbourne School of Population and Global Health, The University of Melbourne, Victoria, Australia.
Karolina KrysinskaCentre for Mental Health, Melbourne School of Population and Global Health, The University of Melbourne, Victoria, Australia.ORCID https://orcid.org/0000-0002-7033-6904
Karl AndriessenCentre for Mental Health, Melbourne School of Population and Global Health, The University of Melbourne, Victoria, Australia.ORCID https://orcid.org/0000-0002-3107-1114
Piumee BandaraTranslational Health Research Institute, Western Sydney University, New South Wales, Australia.
Andrew PageTranslational Health Research Institute, Western Sydney University, New South Wales, Australia.
Marisa SchlichthorstCentre for Mental Health, Melbourne School of Population and Global Health, The University of Melbourne, Victoria, Australia.
Jane PirkisCentre for Mental Health, Melbourne School of Population and Global Health, The University of Melbourne, Victoria, Australia.
Cathrine MihalopoulosHealth Economics Division, School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.
Greg CarterSchool of Medicine and Public Health, University of Newcastle, New South Wales, Australia.
Lennart ReifelsCentre for Mental Health, Melbourne School of Population and Global Health, The University of Melbourne, Victoria, Australia.ORCID https://orcid.org/0000-0001-7844-5163
The University of Melbourne · AUMonash University · AUTranslational Research Institute · AUUniversity of Newcastle Australia · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPrior self-harm represents the most significant risk factor for future self-harm or suicide.

aimTo evaluate the cost-effectiveness of a theoretical brief aftercare intervention (involving brief follow-up contact, care coordination and safety planning), following a hospital-treated self-harm episode, for reducing repeated self-harm within the Australian context.

methodWe employed economic modelling techniques to undertake: (a) a return-on-investment analysis, which compared the cost-savings generated by the intervention with the overall cost of implementing the intervention; and (b) a cost-utility analysis, which compared the net costs of the intervention with health outcomes measured in quality-adjusted life years (QALYs). We considered cost offsets associated with hospital admission for self-harm and the cost of suicide over a period of 10 years in the base case analysis. Uncertainty and one-way sensitivity analyses were also conducted.

resultsThe brief aftercare intervention resulted in net cost-savings of AUD$7.5 M (95% uncertainty interval: -56.2 M to 15.1 M) and was associated with a gain of 222 (95% uncertainty interval: 45 to 563) QALYs over a 10-year period. The estimated return-on-investment ratio for the intervention's modelled cost in relation to cost-savings was 1.58 (95% uncertainty interval: -0.17 to 5.33). Eighty-seven per cent of uncertainty iterations showed that the intervention could be considered cost-effective, either through cost-savings or with an acceptable cost-effectiveness ratio of 50 000 per QALY gained. The results remained robust across sensitivity analyses.

conclusionsA theoretical brief aftercare intervention is highly likely to be cost-effective for preventing suicide and self-harm among individuals with a history of self-harm.

Indexed as

Brief aftercare interventioncost-effectivenessself-harmsuicidesuicide attempt

Identifiers

PMID37525591
PMCPMC10486225
OpenAlexW4385441611

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.