Evidence map›Paper›PMID 37530646›Full record

ArticleThe Kaohsiung journal of medical sciences2023

Klf6 aggravates myocardial ischemia/reperfusion injury by activating Acsl4-mediated ferroptosis.

Ma-Li Qiu, Wei Yan, Mo-Mu Liu

Open access · goldAbstract read
In one paragraph

Article in The Kaohsiung journal of medical sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. The impact of lipid metabolism on ferroptosis in myocardial ischemia-reperfusion injury.Apoptosis : an international journal on programmed cell death · 2025
    Review
  3. Article
  4. Review
  5. Identification of mDiscover oncology · 2025
    Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Ma-Li QiuAttending of Cardiovascular Surgery ICU at the Second Xiangya Hospital of Hunan Province, Changsha, Hunan Province, China.
Wei YanPhysician of Cardiopulmonary bypass specialty at the Second Xiangya Hospital of Hunan Province, Changsha, Hunan Province, China.
Mo-Mu LiuAttending of Cardiovascular Surgery ICU at the Second Xiangya Hospital of Hunan Province, Changsha, Hunan Province, China.ORCID https://orcid.org/0000-0001-7829-8378
Central South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ferroptosis is closely related to myocardial ischemia/reperfusion (I/R) damage. Kruppel-like factor 6 (Klf6) can aggravate renal I/R injury. We aimed to elucidate the role of Klf6 in myocardial I/R damage as well as its potential mechanism. Myocardial I/R mice model and hypoxia/reoxygenation (H/R)-treated HL-1 cells were established. The levels of Fe

Indexed as

Acsl4ferroptosisKlf6m6A modificationmyocardial ischemia/reperfusion

Identifiers

PMID37530646
PMCPMC11895878
OpenAlexW4385476429

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.