Evidence map›Paper›PMID 37532787›Full record

ArticleLeukemia2023

EZH2 targeting induces CD38 upregulation and response to anti-CD38 immunotherapies in multiple myeloma.

Djamila Chemlal, Emmanuel Varlet, Amelie Machura, Sara Ovejero, Guilhem Requirand, Nicolas Robert, Guillaume Cartron, Elina Alaterre, Caroline Bret, Laure Vincent and 5 more

Abstract readLetter
In one paragraph

Article in Leukemia, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Djamila Chemlal *Diag2Tec, Montpellier, France.
Emmanuel Varlet *Institute of Human Genetics, UMR CNRS-UM, 9002, Montpellier, France.
Amelie MachuraDiag2Tec, Montpellier, France.
Sara OvejeroInstitute of Human Genetics, UMR CNRS-UM, 9002, Montpellier, France.
Guilhem RequirandDepartment of Biological Hematology, CHU Montpellier, Montpellier, France.
Nicolas RobertDepartment of Biological Hematology, CHU Montpellier, Montpellier, France.
Guillaume CartronDepartment of Clinical Hematology, CHU Montpellier, Montpellier, France.
Elina AlaterreInstitute of Human Genetics, UMR CNRS-UM, 9002, Montpellier, France.
Caroline BretInstitute of Human Genetics, UMR CNRS-UM, 9002, Montpellier, France.
Laure VincentDepartment of Clinical Hematology, CHU Montpellier, Montpellier, France.ORCID 0000-0001-5904-1286
Charles HerbauxInstitute of Human Genetics, UMR CNRS-UM, 9002, Montpellier, France.ORCID 0000-0003-4910-476X
Giacomo CavalliInstitute of Human Genetics, UMR CNRS-UM, 9002, Montpellier, France.ORCID 0000-0003-3709-3469
Angélique BruyerDiag2Tec, Montpellier, France.
Hugues De BoussacDiag2Tec, Montpellier, France.
Jerome MoreauxInstitute of Human Genetics, UMR CNRS-UM, 9002, Montpellier, France. jerome.moreaux@igh.cnrs.fr.ORCID 0000-0002-5717-3207

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Multiple MyelomaADP-ribosyl Cyclase 1Antibodies, MonoclonalEnhancer of Zeste Homolog 2 ProteinHumansImmunotherapyUp-RegulationADP-ribosyl Cyclase 1Antibodies, MonoclonalEnhancer of Zeste Homolog 2 ProteinEZH2 protein, human

Identifiers

PMID37532787
PMCPMC10457196

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.