Evidence map›Paper›PMID 37534159›Full record

ArticleiScience2023

Tissue specificity of oncogenic BRAF targeted to lung and thyroid through a shared lineage factor.

Elin Schoultz, Shawn Liang, Therese Carlsson, Stefan Filges, Anders Ståhlberg, Henrik Fagman, Clotilde Wiel, Volkan Sayin, Mikael Nilsson

Open access · goldAbstract read
In one paragraph

Article in iScience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Elin SchoultzSahlgrenska Center for Cancer Research, University of Gothenburg, Göteborg, Sweden.
Shawn LiangSahlgrenska Center for Cancer Research, University of Gothenburg, Göteborg, Sweden.
Therese CarlssonSahlgrenska Center for Cancer Research, University of Gothenburg, Göteborg, Sweden.
Stefan FilgesSahlgrenska Center for Cancer Research, University of Gothenburg, Göteborg, Sweden.
Anders StåhlbergSahlgrenska Center for Cancer Research, University of Gothenburg, Göteborg, Sweden.
Henrik FagmanSahlgrenska Center for Cancer Research, University of Gothenburg, Göteborg, Sweden.
Clotilde WielSahlgrenska Center for Cancer Research, University of Gothenburg, Göteborg, Sweden.
Volkan SayinSahlgrenska Center for Cancer Research, University of Gothenburg, Göteborg, Sweden.
Mikael NilssonSahlgrenska Center for Cancer Research, University of Gothenburg, Göteborg, Sweden.
Sahlgrenska University Hospital · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cells of origin in cancer determine tumor phenotypes, but whether lineage-defining transcription factors might influence tissue specificity of tumorigenesis among organs with similar developmental traits are unknown. We demonstrate here that tumor development and progression markedly differ in lung and thyroid targeted by

Indexed as

CancerCell biologyGenetics

Identifiers

PMID37534159
PMCPMC10391731
OpenAlexW4380049831

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.