Evidence mapPaperPMID 37534232Full record

ArticleClinical interventions in aging2023

Development and Validation of Prediction Models for All-Cause Mortality and Cardiovascular Mortality in Patients on Hemodialysis: A Retrospective Cohort Study in China.

Min Yang, Yaqin Yang, Yuntong Xu, Yuchi Wu, Jiarong Lin, Jianling Mai, Kunyang Fang, Xiangxia Ma, Chuan Zou, Qizhan Lin

Abstract read
In one paragraph

Article in Clinical interventions in aging, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Min Yang *The Second Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, People's Republic of China.ORCID 0000-0001-8119-801X
Yaqin Yang *The Second Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, People's Republic of China.
Yuntong XuThe Second Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, People's Republic of China.ORCID 0009-0008-5079-0449
Yuchi WuThe Second Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, People's Republic of China.ORCID 0000-0003-4974-0758
Jiarong LinThe Second Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, People's Republic of China.ORCID 0009-0005-2217-6976
Jianling MaiThe Second Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, People's Republic of China.ORCID 0009-0007-0647-5786
Kunyang FangThe Second Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, People's Republic of China.ORCID 0009-0007-5508-6058
Xiangxia MaThe Second Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, People's Republic of China.
Chuan ZouThe Second Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, People's Republic of China.ORCID 0000-0002-3182-7276
Qizhan LinThe Second Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, People's Republic of China.ORCID 0000-0002-7952-4346

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: This study aimed to develop two predictive nomograms for the assessment of long-term survival status in hemodialysis (HD) patients by examining the prognostic factors for all-cause mortality and cardiovascular (CVD) event mortality. Patients and methods: A total of 551 HD patients with an average age of over 60 were included in this study. The patients' medical records were collected from our hospital and randomly allocated to two cohorts: the training cohort (n=385) and the validation cohort (n=166). We employed multivariate Cox assessments and fine-gray proportional hazards models to explore the predictive factors for both all-cause mortality and cardiovascular event mortality risk in HD patients. Two nomograms were established based on predictive factors to forecast patients' likelihood of survival for 3, 5, and 8 years. The performance of both models was evaluated using the area under the curve (AUC), calibration plots, and decision curve analysis. Results: The nomogram for all-cause mortality prediction included seven factors: age ≥ 60, sex (male), history of diabetes and coronary artery disease, diastolic blood pressure, total triglycerides (TG), and total cholesterol (TC). The nomogram for cardiovascular event mortality prediction included three factors: history of diabetes and coronary artery disease, and total cholesterol (TC). Both models demonstrated good discrimination, with AUC values of 0.716, 0.722 and 0.725 for all-cause mortality at 3, 5, and 8 years, respectively, and 0.702, 0.695, and 0.677 for cardiovascular event mortality, respectively. The calibration plots indicated a good agreement between the predictions and the decision curve analysis demonstrated a favorable clinical utility of the nomograms. Conclusion: Our nomograms were well-calibrated and exhibited significant estimation efficiency, providing a valuable predictive tool to forecast prognosis in HD patients.

Indexed as

Coronary Artery DiseaseCholesterolFemaleHumansMaleMiddle AgedNomogramsPrognosisRetrospective StudiesCholesterolall-causecardiovascularhemodialysismodelmortalitynomogram

Identifiers

PMID37534232
PMCPMC10392814

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.