Evidence map›Paper›PMID 37534513›Full record

ArticleLupus science & medicine2023

Lupus spectrum ambiguity has long-term negative implications for patients.

Ian N Bruce, Joy Buie, Lauren Bloch, Sang-Cheol Bae, Karen Costenbader, Roger A Levy, Victoria P Werth, Ashley Marion, Sanjyot Sangodkar, Susan Manzi

Abstract read
In one paragraph

Article in Lupus science & medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. REDEFINING AUTOIMMUNE DISEASES: THE OPPORTUNITY FOR PRECISION AND PREVENTION.Transactions of the American Clinical and Climatological Association · 2025
    Review
  10. Review
  11. Article
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ian N BruceRheumatology, The University of Manchester, Manchester, UK.ORCID 0000-0003-3047-500X
Joy BuieResearch, Lupus Foundation of America, Washington, District of Columbia, USA buie@lupus.org.ORCID 0000-0003-4026-4812
Lauren BlochHealth Policy and Regulatory Affairs, Faegre Drinker Biddle and Reath, Washington, District of Columbia, USA.
Sang-Cheol BaeRheumatology, Hanyang University Seoul Hospital, Seoul, Korea (the Republic of).ORCID 0000-0003-4658-1093
Karen CostenbaderMedicine, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Roger A LevyGlobal Medical Expert Immunology and Specialty Medicine, GlaxoSmithKline, Collegeville, Pennsylvania, USA.ORCID 0000-0001-6393-6031
Victoria P WerthDermatology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID 0000-0003-3030-5369
Ashley MarionResearch, Lupus Foundation of America, Washington, District of Columbia, USA.
Sanjyot SangodkarStrategy and Consulting, Faegre Drinker Consulting, Washington, District of Columbia, USA.
Susan ManziLupus Center of Excellence, Autoimmunity Institute, Allegheny Health Network, Pittsburgh, Pennsylvania, USA.ORCID 0000-0002-0803-6150

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lupus is a complex disease that is often difficult to diagnose. Risks of diagnostic delays include non-specific signs and symptoms that mimic other diseases and a lack of diagnostic criteria and referral pathways for non-specialists. To address these issues, we convened a series of virtual meetings with members of our Addressing Lupus Pillars for Health Advancement clinical care team. Meeting participants included lupus physicians, treatment developers from biotechnology, patient advocacy group representatives from the Lupus Foundation of America and advocacy/government consultants. Causes and consequences of ambiguity in diagnosis and diagnostic delays were evaluated through historical, experiential and evidence-based accounts (survey data, literature reviews and patient testimonials). Discussions highlighted the need for a clearer understanding of the definition of lupus, the natural history of the disease and the need for advancements in biotechnology to support an accurate and timely diagnosis with the potential development of a lupus spectrum.

Indexed as

Lupus Erythematosus, SystemicPhysiciansHumansAutoimmune DiseasesInflammationLupus Erythematosus, SystemicOutcome Assessment, Health CarePatient Care Team

Identifiers

PMID37534513
PMCPMC9835935

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.