Evidence map›Paper›PMID 37535890›Full record

ReviewJournal of travel medicine2023

Influenza: seasonality and travel-related considerations.

Loukas Kakoullis, Robert Steffen, Albert Osterhaus, Marco Goeijenbier, Sowmya R Rao, Satoshi Koiso, Emily P Hyle, Edward T Ryan, Regina C LaRocque, Lin H Chen

Abstract readReview
In one paragraph

Review in Journal of travel medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Extended influenza seasons in Australia and New Zealand in 2025 due to the emergence of influenza A(H3N2) subclade K viruses.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Ear, nose and throat disorders and international travel.Tropical diseases, travel medicine and vaccines · 2025
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Loukas KakoullisDepartment of Medicine, Mount Auburn Hospital, Cambridge, MA 02138, USA.ORCID 0000-0001-6245-1569
Robert SteffenEpidemiology, Biostatistics and Prevention Institute, University of Zurich, Zurich, 8001, Switzerland.
Albert OsterhausResearch Center Emerging Infections and Zoonoses, University of Veterinary Medicine, Hannover, 30559, Germany.
Marco GoeijenbierDepartment of Intensive Care, Spaarne Gasthuis, Haarlem, 2035, Netherlands.
Sowmya R RaoDepartment of Global Health, Boston University, Boston, MA 02118, USA.
Satoshi KoisoMedical Practice Evaluation Center, Massachusetts General Hospital, Boston, MA 02114, USA.ORCID 0000-0001-7542-1801
Emily P HyleHarvard Medical School, Boston, MA 02115, USA.
Edward T RyanHarvard Medical School, Boston, MA 02115, USA.
Regina C LaRocqueHarvard Medical School, Boston, MA 02115, USA.ORCID 0000-0003-4558-0339
Lin H ChenDepartment of Medicine, Mount Auburn Hospital, Cambridge, MA 02138, USA.ORCID 0000-0002-5684-8436

Funding

CDC HHS U01CK000633NCEZID CDC HHS U01 CK000633
6 · The paper itself

Abstract

rationale for reviewThis review aims to summarize the transmission patterns of influenza, its seasonality in different parts of the globe, air travel- and cruise ship-related influenza infections and interventions to reduce transmission. KEY

findingsThe seasonality of influenza varies globally, with peak periods occurring mainly between October and April in the northern hemisphere (NH) and between April and October in the southern hemisphere (SH) in temperate climate zones. However, influenza seasonality is significantly more variable in the tropics. Influenza is one of the most common travel-related, vaccine-preventable diseases and can be contracted during travel, such as during a cruise or through air travel. Additionally, travellers can come into contact with people from regions with ongoing influenza transmission. Current influenza immunization schedules in the NH and SH leave individuals susceptible during their respective spring and summer months if they travel to the other hemisphere during that time. CONCLUSIONS/RECOMMENDATIONS: The differences in influenza seasonality between hemispheres have substantial implications for the effectiveness of influenza vaccination of travellers. Health care providers should be aware of influenza activity when patients report travel plans, and they should provide alerts and advise on prevention, diagnostic and treatment options. To mitigate the risk of travel-related influenza, interventions include antivirals for self-treatment (in combination with the use of rapid self-tests), extending the shelf life of influenza vaccines to enable immunization during the summer months for international travellers and allowing access to the influenza vaccine used in the opposite hemisphere as a travel-related vaccine. With the currently available vaccines, the most important preventive measure involves optimizing the seasonal influenza vaccination. It is also imperative that influenza is recognized as a travel-related illness among both travellers and health care professionals.

Indexed as

Air TravelInfluenza, HumanInfluenza VaccinesHumansImmunization ScheduleSeasonsTravel-Related IllnessVaccinationInfluenza Vaccinesantiviralcruise shipoutbreakRespiratory virusscreeningtransmissionvaccination

Identifiers

PMID37535890
PMCPMC11758160

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.