Evidence map›Paper›PMID 37536964›Full record

SynthesisBMJ open2023

Development of a complex exercise rehabilitation intervention for people with pulmonary hypertension: the supervised pulmonary hypertension exercise rehabilitation (SPHERe) trial.

Stuart Ennis, Harbinder Kaur Sandhu, Julie Bruce, Kate Seers, Tamar Pincus, Martin Underwood, Gordon McGregor

Open access · goldAbstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in BMJ open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Stuart EnnisClinical Trials Unit, Warwick Medical School, University of Warwick, Coventry, UK stuart.ennis@warwick.ac.uk.ORCID 0000-0002-7176-6252
Harbinder Kaur SandhuClinical Trials Unit, Warwick Medical School, University of Warwick, Coventry, UK.ORCID 0000-0003-1522-8078
Julie BruceClinical Trials Unit, Warwick Medical School, University of Warwick, Coventry, UK.ORCID 0000-0002-8462-7999
Kate SeersRoyal College of Nursing Research Institute, Warwick Medical School, University of Warwick, Coventry, UK.ORCID 0000-0001-7921-552X
Tamar PincusDepartment of Psychology, Royal Hollaway University, London, UK.
Martin UnderwoodClinical Trials Unit, Warwick Medical School, University of Warwick, Coventry, UK.
Gordon McGregorClinical Trials Unit, Warwick Medical School, University of Warwick, Coventry, UK.ORCID 0000-0001-8963-9107
University of Warwick · GBUniversity Hospitals Coventry and Warwickshire NHS Trust · GBRoyal College of Nursing · GBRoyal Holloway University of London · GB

Funding

Department of Health
6 · The paper itself

Abstract

backgroundPeople with pulmonary hypertension (PH) are not routinely referred for exercise rehabilitation despite the potential for reducing breathlessness and improving quality of life. We describe the development of a supervised pulmonary hypertension exercise rehabilitation (SPHERe) programme for people with PH.

methodsDevelopment was completed in three phases: (1) systematic review, (2) stakeholder engagement with consensus from patients and experts and (3) prepilot intervention acceptability testing. We completed systematic reviews to identify international cardiopulmonary rehabilitation guidance and trials of exercise-based interventions for people with PH. Evidence from systematic reviews and stakeholder consensus shaped the SPHERe intervention, including addition of individual behavioural support sessions to promote exercise adherence. The draft SPHERe intervention was ratified through discussions with multidisciplinary professionals and people living with PH. We acceptability tested the centre-based intervention with eight participants in a prepilot development phase which identified a number of condition-specific issues relating to safety and fear avoidance of activity. Comprehensive intervention practitioner training manuals were produced to ensure standardised delivery. Participant workbooks were developed and piloted. Trial recruitment began in January 2020 but was subsequently suspended in March 2020 further to COVID-19 pandemic 'lockdowns'. In response to the pandemic, we undertook further development work to redesign the intervention to be suitable for exclusively home-based online delivery. Recruitment to the revised protocol began in June 2021. DISCUSSION: The final SPHERe intervention incorporated weekly home-based online group exercise and behavioural support 'coaching' sessions supervised by trained practitioners, with a personalised home exercise plan and the optional loan of a stationary exercise bike. The intervention was fully manualised with clear pathways for assessment and individualised exercise prescription. The clinical and cost-effectiveness of the SPHERe online rehabilitation intervention is currently being tested in a UK multicentre randomised controlled trial. TRIAL REGISTRATION NUMBER: ISCRTN10608766.

Indexed as

COVID-19Hypertension, PulmonaryCommunicable Disease ControlExercise TherapyHumansPandemicsQuality of Lifecardiologyrehabilitation medicinerespiratory medicine (see thoracic medicine)

Identifiers

PMID37536964
PMCPMC10401230
OpenAlexW4385525222

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.