Evidence map›Paper›PMID 37539093›Full record

ArticleJournal of radiology and oncology2023

Nanometer-scale distribution of PD-1 in the melanoma tumor microenvironment.

Colin J Comerci, Dannielle G McCarthy, Mehdi Nosrati, Kevin B Kim, Mohammed Kashani-Sabet, W E Moerner, Stanley P Leong

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of radiology and oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Colin J ComerciDepartment of Chemistry, Stanford University, Stanford, CA, 94305, USA.
Dannielle G McCarthyDepartment of Chemistry, Stanford University, Stanford, CA, 94305, USA.
Mehdi NosratiCenter for Melanoma Research and Treatment, California Pacific Medical Center, Research Institute, San Francisco, CA, 94107, USA.
Kevin B KimCenter for Melanoma Research and Treatment, California Pacific Medical Center, Research Institute, San Francisco, CA, 94107, USA.
Mohammed Kashani-SabetCenter for Melanoma Research and Treatment, California Pacific Medical Center, Research Institute, San Francisco, CA, 94107, USA.
W E MoernerDepartment of Chemistry, Stanford University, Stanford, CA, 94305, USA.
Stanley P LeongCenter for Melanoma Research and Treatment, California Pacific Medical Center, Research Institute, San Francisco, CA, 94107, USA.
California Pacific Medical Center · USStanford University · USUniversity of California, San Diego · US

Funding

Single-Molecule Imaging for Cell Biology and Super-Resolution MicroscopyR35GM118067 · NIGMS · STANFORD UNIVERSITY · PI MOERNER, WILLIAM E · 2016 to 2025
$6.2M
NIGMS NIH HHS R35 GM118067
6 · The paper itself

Abstract

The nanometer-scale spatial organization of immune receptors plays a role in cell activation and suppression. While the connection between this spatial organization and cell signaling events is emerging from cell culture experiments, how these results translate to more physiologically relevant settings like the tumor microenvironment remains poorly understood due to the challenges of high-resolution imaging

Indexed as

Immune checkpoint inhibitorMelanomaPD-1Super-resolution fluorescence microscopyTumor microenvironment

Identifiers

PMID37539093
PMCPMC10399701
OpenAlexW4377103766

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.