Evidence map›Paper›PMID 37540408›Full record

ArticleClinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico2023

SEOM-GEINO clinical guidelines for high-grade gliomas of adulthood (2022).

Pedro Pérez Segura, Noelia Vilariño Quintela, María Martínez García, Sonia Del Barco Berrón, Regina Gironés Sarrió, Jesús García Gómez, Almudena García Castaño, Luis Miguel Navarro Martín, Oscar Gallego Rubio, Estela Pineda Losada

Abstract read
In one paragraph

Article in Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Post-recurrence management of malignant glial brain tumors: therapeutic strategies, evidence and limitations, palliative care, terminal sedation, and end-of-life considerations.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Pedro Pérez SeguraMedical Oncology Department, Hospital Clínico San Carlos, IdISCC, Madrid, Spain.
Noelia Vilariño QuintelaMedical Oncology Department, Catalan Institute of Oncology, Barcelona, Spain.
María Martínez GarcíaMedical Oncology Department, Hospital del Mar, Barcelona, Spain.
Sonia Del Barco BerrónMedical Oncology Department, Unidad Cáncer de Mama y Tumores Cerebrales, Instituto Catalán de Oncologia, Hospital Universitario Doctor Josep Trueta, Girona, Spain.
Regina Gironés SarrióMedical Oncology Department. Hospital, Univeristari i Politècnic La Fe, Valencia, Spain.
Jesús García GómezMedical Oncology Department, Complejo Hospitalario Universitario de Orense, Orense, Spain.
Almudena García CastañoMedical Oncology Department, Hospital Universitario Marqués de Valdecilla, Santander, Spain.
Luis Miguel Navarro MartínMedical Oncology Department, Complejo Asistencial Universitario de Salamanca, Salamanca, Spain.
Oscar Gallego RubioMedical Oncology Department, Hospital de Sant Pau i La Santa Creu, Barcelona, Spain.
Estela Pineda LosadaMedical Oncology Department, Hospital Clinic and Translational Genomics and Targeted Therapies in Solid Tumors, IDIBAPS, Barcelona, Spain. epineda@clinic.cat.ORCID http://orcid.org/0000-0003-2128-747X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

High-grade gliomas (HGG) are the most common primary brain malignancies and account for more than half of all malignant primary brain tumors. The new 2021 WHO classification divides adult HGG into four subtypes: grade 3 oligodendroglioma (1p/19 codeleted, IDH-mutant); grade 3 IDH-mutant astrocytoma; grade 4 IDH-mutant astrocytoma, and grade 4 IDH wild-type glioblastoma (GB). Radiotherapy (RT) and chemotherapy (CTX) are the current standard of care for patients with newly diagnosed HGG. Several clinically relevant molecular markers that assist in diagnosis and prognosis have recently been identified. The treatment for recurrent high-grade gliomas is not well defined and decision-making is usually based on prior strategies, as well as several clinical and radiological factors. Whereas the prognosis for GB is grim (5-year survival rate of 5-10%) outcomes for the other high-grade gliomas are typically better, depending on the molecular features of the tumor. The presence of neurological deficits and seizures can significantly impact quality of life.

Indexed as

Brain NeoplasmsGlioblastomaGliomaAdultHumansMutationNeoplasm Recurrence, LocalQuality of LifeEpidemiologyHigh-grade gliomasManagementMolecularTreatment

Identifiers

PMID37540408
PMCPMC10425506

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.