Evidence map›Paper›PMID 37540503›Full record

ArticleACS sensors2023

Triplet-Triplet Annihilation Upconversion-Based Oxygen Sensors to Overcome the Limitation of Autofluorescence.

Adrian A Mendonsa, Cassandra C Soeldner, Natalie E Mudd, Samuel C Saccomano, Kevin J Cash

Abstract read
In one paragraph

Article in ACS sensors, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Adrian A MendonsaChemical and Biological Engineering, Colorado School of Mines, Golden, Colorado 80401, United States.ORCID 0000-0002-6817-9778
Cassandra C SoeldnerChemical and Biological Engineering, Colorado School of Mines, Golden, Colorado 80401, United States.ORCID 0000-0002-5475-0056
Natalie E MuddQuantitative Biosciences and Engineering, Colorado School of Mines, Golden, Colorado 80401, United States.ORCID 0000-0002-9969-7615
Samuel C SaccomanoChemical and Biological Engineering, Colorado School of Mines, Golden, Colorado 80401, United States.ORCID 0000-0001-9105-2663
Kevin J CashChemical and Biological Engineering, Colorado School of Mines, Golden, Colorado 80401, United States.ORCID 0000-0002-9748-2530

Funding

Nanosensors to study invertebrate functional hypoxia and electrolyte regulationR15GM140443 · NIGMS · COLORADO SCHOOL OF MINES · PI CASH, KEVIN JOSEPH · 2020 to 2020
$419k
NIGMS NIH HHS R15 GM140443
6 · The paper itself

Abstract

Autofluorescence is one of the many challenges in bioimaging as it can mask the emission from fluorescent probes or markers, a limitation that can be overcome via upconversion. Herein, we have developed a nanosensor that uses triplet-triplet annihilation upconversion to optically report changes in the dissolved oxygen concentration. Using a sensitizer-annihilator dye pairing of platinum(II) octaethylporphyrin and 9,10-diphenylanthracene, we monitored the oxygen consumption (as a proxy for metabolic activity) over time in a biological system─

Indexed as

Fluorescent DyesSaccharomyces cerevisiaeOxygenFluorescent DyesOxygenautofluorescencenanosensoroxygentriplet−triplet annihilationupconversion

Identifiers

PMID37540503
PMCPMC10566256

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.