Evidence mapPaperPMID 37540689Full record

ArticlePloS one2023

Assessment of health-related quality of life among patients with obesity, hypertension and type 2 diabetes mellitus and its relationship with multimorbidity.

Shahid Shah, Ghulam Abbas, Ayesha Aslam, Fawad Ahmad Randhawa, Faiz Ullah Khan, Haris Khurram, Usman Rashid Chand, Muhammad Hammad Butt, Tauqeer Hussain Mallhi, Yusra Habib Khan

Abstract read
In one paragraph

Article in PloS one, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Shahid ShahFaculty of Pharmaceutical Sciences, Department of Pharmacy Practice, Government College University Faisalabad, Faisalabad, Pakistan.ORCID 0000-0002-7396-8341
Ghulam AbbasFaculty of Pharmaceutical Sciences, Department of Pharmaceutics, Government College University Faisalabad, Faisalabad, Pakistan.
Ayesha AslamDepartment of Neurology, King Edward Medical University, Lahore, Pakistan.
Fawad Ahmad RandhawaDepartment of Endocrinology, King Edward Medical University, Lahore, Pakistan.
Faiz Ullah KhanDepartment of Pharmacy Administration and Clinical Pharmacy, School of Pharmacy, Xi'an Jiaotong University, Xi'an, China.
Haris KhurramNational University of Computer and Emerging Sciences, Chiniot-Faisalabad Campus, Chiniot, Pakistan.ORCID 0000-0003-1814-4742
Usman Rashid ChandFaculty of Pharmaceutical Sciences, Department of Pharmacy Practice, Government College University Faisalabad, Faisalabad, Pakistan.
Muhammad Hammad ButtFaculty of Pharmacy, Department of Medicinal Chemistry, Uppsala University, Uppsala, Sweden.ORCID 0000-0003-4387-1351
Tauqeer Hussain MallhiDepartment of Clinical Pharmacy, College of Pharmacy, Jouf University, Sakaka, Saudi Arabia.
Yusra Habib KhanDepartment of Clinical Pharmacy, College of Pharmacy, Jouf University, Sakaka, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Obesity, hypertension (HTN) and type 2 diabetes (T2D) are among the multifactorial disorders that occur at higher prevalence in a population. This study aims to assess the health-related quality of life (HRQoL) of patients with obesity, HTN and T2D individually and in the form of multimorbidity. A questionnaire-based cross-sectional study was conducted among the patients in 15 private clinics of Punjab, Pakistan. A stratified random sampling technique was used to collect the data from patients with obesity, HTN and T2D or their comorbidity. A total of 1350 patients responded by completing the questionnaire. The HRQoL of these patients was assessed using the EQ-5D-5L questionnaire (a standardized instrument for measuring generic health status). Statistical analysis was performed using chi-square test, Mann-Whitney U test, and Kruskal-Wallis test. Multivariate linear regression model was used to model the visual analogue scale (VAS) score. In total, 15% of patients had combined obesity, HTN and T2D; 16.5% had HTN and T2D; 13.5% had obesity and HTN and 12.8% had obesity and T2D. Only 15.8% of patients had obesity, 14.3% had HTN, and 12% had T2D. Mann Whitney-U test gave the statistically significant (p = <0.001) HRQoL VAS score55.1 (±23.2) of patients with the obesity. HRQoL VAS scores of patients with obesity were found to be higher when compared to patients with both T2D 49.8 (±15.4) and HTN 48.2 (±21). Diagnosis of one, two and three diseases showed significant results in VAS with all variables including gender (p = 0.004), educational level (p = <0.001), marital status (p<0.001), residence (p = <0.001), financial situation (p = <0.001) and monthly income (p = <0.001). The most frequently observed extremely problematic dimension was anxiety/ depression (47%) and the self-care (10%) was the least affected. Patient HRQoL is decreased by T2D, HTN, and obesity. The impact of these diseases coexisting is more detrimental to HRQoL.

Indexed as

Diabetes Mellitus, Type 2HypertensionCross-Sectional StudiesHumansMultimorbidityObesityQuality of LifeSurveys and Questionnaires

Identifiers

PMID37540689
PMCPMC10403106

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.