Evidence map›Paper›PMID 37541329›Full record

ArticleTransplantation and cellular therapy2023

Financial Hardship in Childhood Cancer Survivors Treated with Hematopoietic Cell Transplantation: A Report from the Childhood Cancer Survivor Study.

David Buchbinder, Neel S Bhatt, Huiqi Wang, Yutaka Yasui, Saro Armenian, Smita Bhatia, Eric J Chow, I-Chan Huang, Anne C Kirchoff, Wendy Leisenring and 5 more

Open access · greenAbstract read
In one paragraph

Article in Transplantation and cellular therapy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 10 institutions in 2 countries.

David BuchbinderDepartment of Pediatrics, University of California at Irvine, Irvine, California; Division of Hematology, Oncology at Children's Hospital of Orange County, Orange, California. Electronic address: dbuchbinder@choc.org.
Neel S BhattClinical Research Division, Fred Hutchinson Cancer Center, Seattle, Washington.
Huiqi WangDepartment of Epidemiology and Cancer Control, St Jude Children's Research Hospital, Memphis, Tennessee.
Yutaka YasuiDepartment of Epidemiology and Cancer Control, St Jude Children's Research Hospital, Memphis, Tennessee.
Saro ArmenianDepartment of Pediatrics, City of Hope Comprehensive Cancer Center, Duarte, California.
Smita BhatiaInstitute for Cancer Outcomes and Survivorship, University of Alabama at Birmingham, Birmingham, Alabama.
Eric J ChowClinical Research Division, Fred Hutchinson Cancer Center, Seattle, Washington.
I-Chan HuangDepartment of Epidemiology and Cancer Control, St Jude Children's Research Hospital, Memphis, Tennessee.
Anne C KirchoffCancer Control and Population Sciences, Huntsman Cancer Institute, Salt Lake City, Utah; Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, Utah.
Wendy LeisenringClinical Research Division, Fred Hutchinson Cancer Center, Seattle, Washington.
Elyse R ParkMongan Institute, Harvard Medical School, Boston, Massachusetts.
K Robin YabroffSurveillane and Health Equity Science, American Cancer Society, Atlanta, Georgia.
Gregory T ArmstrongDepartment of Epidemiology and Cancer Control, St Jude Children's Research Hospital, Memphis, Tennessee.
Paul C NathanInstitute of Health Policy, Management and Evaluation, The University of Toronto, Toronto, Ontario, Canada; Division of Hematology, Oncology, The Hospital for Sick Children, Toronto, Ontario, Canada.
Nandita KheraDivision of Hematology and Oncology, Mayo Clinic, Phoenix, Arizona.
St. Jude Children's Research Hospital · USFred Hutch Cancer Center · USAmerican Cancer Society · USChildren's Hospital of Orange County · USCity of Hope · USHarvard University · USUniversity of Alabama at Birmingham · USUniversity of Toronto · CAUniversity of Utah · USWinnMed · US

Funding

Mach-LETSGO: Machine-LEarning of Treatment, Survey, and Genetics towards Obtaining Correct Classification of Chronic Conditions in Adult Survivors in the Childhood Cancer Survivor Study - CCSS SupplU24CA055727 · NCI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI Gregory Armstrong · 1999 to 2026
$96.7M
NCI NIH HHS U24 CA055727
6 · The paper itself

Abstract

Long-term survivors of childhood cancer are at risk for financial hardship. However, it is not known if HCT leads to an incremental change in financial hardship for survivors who received it versus those who did not. We examined financial outcomes among adult survivors of childhood cancer who had undergone HCT. Using a cross-sectional survey in the Childhood Cancer Survivor Study population between 2017 and 2019, self-reported financial hardship was compared between survivors who received HCT, survivors treated without HCT ("non-HCT"), and siblings and categorized into 3 domains: material hardship/financial sacrifices, behavioral, and psychological hardship. The standardized score of each domain of financial hardship was calculated by adding the item responses and dividing by the standard deviation among siblings. Multivariable linear and logistic regression were used to evaluate associations between sociodemographic characteristics, cancer diagnosis, post-treatment complications, and financial hardship among survivors. The mean adjusted score for each hardship domain was not significantly different between HCT survivors (n = 133) and non-HCT survivors (n = 2711); mean differences were .18 (95% confidence interval [CI], -.05 to .41) for material hardship/financial sacrifices, .07 (95% CI, -.18 to .32) for behavioral hardship, and .19 (95% CI, -.04 to .42) for psychological hardship. Within specific items, a higher proportion of survivors treated with HCT reported greater financial hardship compared to non-HCT survivors. HCT survivors also had significantly higher mean domain scores compared to sibling controls (n = 1027) in all domains. Household income and chronic health conditions, but not HCT, were associated with financial hardship among all survivors. Adult survivors of childhood cancer treated with HCT do not report greater overall financial hardship compared to non-HCT survivors but do report greater overall financial hardship compared to sibling controls. Surveillance and intervention may be necessary for all survivors regardless of HCT status.

Indexed as

Cancer SurvivorsHematopoietic Stem Cell TransplantationNeoplasmsAdultCross-Sectional StudiesFinancial StressHumansChildhood cancer survivorFinancial hardshipHematopoietic cell transplantation

Identifiers

PMID37541329
PMCPMC10834839
OpenAlexW4385494067

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.