Evidence map›Paper›PMID 37541364›Full record

ArticleEuropean journal of pharmacology2023

Anti-inflammatory potency of novel ecto-5'-nucleotidase/CD73 inhibitors in astrocyte culture model of neuroinflammation.

Katarina Mihajlovic, Marija Adzic Bukvic, Milorad Dragic, Mirko Scortichini, Kenneth A Jacobson, Nadezda Nedeljkovic

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European journal of pharmacology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Dual CD73/AFrontiers in pharmacology · 2026
    Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Katarina MihajlovicLaboratory for Neurobiology, Department of General Physiology and Biophysics, Faculty of Biology University of Belgrade, Serbia.
Marija Adzic BukvicLaboratory for Neurobiology, Department of General Physiology and Biophysics, Faculty of Biology University of Belgrade, Serbia.
Milorad DragicLaboratory for Neurobiology, Department of General Physiology and Biophysics, Faculty of Biology University of Belgrade, Serbia.
Mirko ScortichiniMolecular Recognition Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, 20892, USA.
Kenneth A JacobsonMolecular Recognition Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, 20892, USA.
Nadezda NedeljkovicLaboratory for Neurobiology, Department of General Physiology and Biophysics, Faculty of Biology University of Belgrade, Serbia. Electronic address: nnedel@bio.bg.ac.rs.
University of Belgrade · RSNational Institutes of Health · US

Funding

Development Of Drugs Acting At Adenosine ReceptorsZIADK031117 · NIDDK · NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES · PI JACOBSON, KENNETH ALAN · 2009 to 2025
$10.4M
Intramural NIH HHS ZIA DK031117
6 · The paper itself

Abstract

Three novel cytosine-derived α,β-methylene diphosphonates designated MRS4598, MRS4552, and MRS4602 were tested in the range of 1 × 10

Indexed as

AstrocytesNeuroinflammatory Diseases5'-NucleotidaseAnti-Inflammatory AgentsHumans5'-NucleotidaseAnti-Inflammatory AgentsAstrocytesCell migrationCytosine-based nucleoside 5'-α,β-methylene diphosphatesEcto-5′-nucleotidase/CD73Shedding

Identifiers

PMID37541364
PMCPMC10527948
OpenAlexW4385491412

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.