Evidence map›Paper›PMID 37541981›Full record

Observational studyWorld journal of surgery2023

Sarcopenia and Sarcopenic Obesity on Body Composition Analysis is a Significant Predictor of Mortality in Severe Acute Pancreatitis: A Longitudinal Observational Study.

Robert Farquhar, Scott Matthews, Nesta Baxter, George Rayers, Chathura B B Ratnayake, Francis P Robertson, Sandip Nandhra, Wei Boon Lim, Miles Witham, Sanjay Pandanaboyana

Open access · hybridAbstract readObservational Study
In one paragraph

Observational study in World journal of surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 16 citations in OpenAlex.

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  11. Clinical and imaging predictors for the development of diabetes mellitus following a single episode of acute pancreatitis in youth.Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Robert FarquharSchool of Medical Education, Newcastle University, Newcastle Upon Tyne, UK. r.farquhar@nhs.net.ORCID 0000-0002-9744-9482
Scott MatthewsDepartment of Surgery, Royal Victoria Infirmary, Newcastle Upon Tyne, UK.
Nesta BaxterSchool of Medical Education, Newcastle University, Newcastle Upon Tyne, UK.
George RayersSchool of Medical Education, Newcastle University, Newcastle Upon Tyne, UK.
Chathura B B RatnayakeDepartment of Surgery, The University of Auckland, Auckland, New Zealand.
Francis P RobertsonHPB and Transplant Unit, Freeman Hospital, Newcastle Upon Tyne, UK.
Sandip NandhraHPB and Transplant Unit, Freeman Hospital, Newcastle Upon Tyne, UK.
Wei Boon LimSchool of Medical Education, Newcastle University, Newcastle Upon Tyne, UK.
Miles WithamPopulation Health Sciences Institute, Newcastle University, Newcastle Upon Tyne, UK.
Sanjay PandanaboyanaHPB and Transplant Unit, Freeman Hospital, Newcastle Upon Tyne, UK.
Newcastle University · GBFreeman Hospital · GBRoyal Victoria Infirmary · GBUniversity of Auckland · NZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe prevalence and impact of sarcopenia and sarcopenic obesity noted on body composition analysis in severe acute pancreatitis (SAP) is unknown. This study investigates the prevalence of sarcopenia at different timepoints and its effect on post-pancreatitis complications and mortality.

methodsA prospective database of SAP admissions with organ failure at a single institution from 2015 to 2019 were analysed. Sarcopenia was determined by IMAGE J software on CT. Database was further queried for post-pancreatitis complications and mortality.

results141 patients with a median age of 59 (range 18-88) and M:F ratio 1.52:1 of were analysed. Sarcopenia was present in 111/141 (79%) patients at admission, 78/79 (99%) at 3 months and 26/36 (72%) at 12 months. 67/111 patients with sarcopenia on admission had sarcopenic obesity. The mortality at 30 days, 3 months and 12 months was 16/141 (11%), 30/141 (21%) and 42/141 (30%) respectively. Mortality was significantly higher in sarcopenic patients at admission (35.14%) compared to the non-sarcopenic group (10%), P = 0.008). Mortality in the sarcopenic obesity group was significantly higher (45%) compared to the sarcopenic non-obese group (20%), P = 0.009) at admission. Multivariate logistic regression identified sarcopenic obesity (OR: 2.880), age (OR: 1.048) and number of organ failures (OR: 3.225) as significant predictors of mortality.

conclusionsSarcopenia and Sarcopenic obesity are highly prevalent in SAP patients on admission and during follow up. Furthermore, sarcopenic obesity was shown to be a significant predictor of mortality at admission, suggesting that body composition analysis could be a potential predictive marker of mortality in SAP patients.

Indexed as

PancreatitisSarcopeniaAcute DiseaseBody CompositionHumansObesity

Identifiers

PMID37541981
PMCPMC10545625
OpenAlexW4385576878

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.