SynthesisBJS open2023
Consensus-defined sarcopenia predicts adverse outcomes after elective abdominal surgery: meta-analysis.
Synthesis in BJS open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed, 29 citations in OpenAlex.
- Frailty and sarcopenia proxies are associated with postoperative outcomes after abdominal wall reconstruction: a national database analysis.Surgical endoscopy · 2026Article
- Comparative contributions of visceral adiposity and muscle-related parameters to postoperative complications after gastrectomy: a domain-based analysis.BMC cancer · 2026Article
- Article
- The impact of frailty and sarcopenia index on postoperative nausea and vomiting in elderly patients undergoing sedation-assisted gastrointestinal endoscopy.BMC anesthesiology · 2026Article
- New Proposal in the Approach to Brachial Remodeling: The Melfa-Anastasia Arm Laxity System (MAALS).Aesthetic surgery journal. Open forum · 2026Article
- Intravenous contrast medium impairs CT-based muscle quality but not quantity assessment: a translational study.Frontiers in radiology · 2026Article
- Preoperative sarcopenia and its impact on postoperative complications in laparoscopic anti-reflux surgery: a clinical analysis.Frontiers in surgery · 2026Article
- The Influence of Muscle Morphology on Oncological Outcomes: A Review.Journal of frailty, sarcopenia and falls · 2025Review
- Relationship Between Oral Intake and Sarcopenia in Patients with Disease-Related Malnutrition.Nutrients · 2025Observational
- Review
- Validation of body composition parameters extracted via deep learning-based segmentation from routine computed tomographies.Scientific reports · 2025Article
- Frailty and body composition predict adverse outcomes after emergency general surgery admission: a multicentre observational cohort study.Annals of the Royal College of Surgeons of England · 2025Observational
- Observational
- Predictive model for sarcopenia in patients with non-small cell lung cancer and malignant pleural effusion.BMC cancer · 2025Article
- Factors influencing changes in body composition and nutritional status in patients with hyperacute stroke: prospective study.Frontiers in nutrition · 2025Article
- Perioperative evaluation of CT-based body composition as predictors of postoperative outcome following pancreaticoduodenectomy.Frontiers in nutrition · 2025Article
- The alkaline phosphatase-to-prealbumin ratio combined with CT-quantified sarcopenia predicts survival in gastric cancer patients after surgical resection.Frontiers in nutrition · 2025Article
- Influence of sarcopenia and frailty in the management of elderly patients with acute appendicitis.World journal of clinical cases · 2024Article
- Article
- Adverse postoperative outcomes in elderly patients with sarcopenia.BMC geriatrics · 2024Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSarcopenia refers to the progressive age- or pathology-associated loss of skeletal muscle. When measured radiologically as reduced muscle mass, sarcopenia has been shown to independently predict morbidity and mortality after elective abdominal surgery. However, the European Working Group on Sarcopenia in Older People (EWGSOP) recently updated their sarcopenia definition, emphasizing both low muscle 'strength' and 'mass'. The aim of this systematic review and meta-analysis was to determine the prognostic impact of this updated consensus definition of sarcopenia after elective abdominal surgery.
methodsMEDLINE, Embase, Scopus, and Cochrane Central Register of Controlled Trials (CENTRAL) databases were systematically searched for studies comparing prognostic outcomes between sarcopenic versus non-sarcopenic adults after elective abdominal surgery from inception to 15 June 2022. The primary outcomes were postoperative morbidity and mortality. Sensitivity analyses adjusting for confounding patient factors were also performed. Methodological quality assessment of studies was performed independently by two authors using the QUality in Prognosis Studies (QUIPS) tool.
resultsTwenty articles with 5421 patients (1059 sarcopenic and 4362 non-sarcopenic) were included. Sarcopenic patients were at significantly greater risk of incurring postoperative complications, despite adjusted multivariate analysis (adjusted OR 1.56, 95 per cent c.i. 1.39 to 1.76). Sarcopenic patients also had significantly higher rates of in-hospital (OR 7.62, 95 per cent c.i. 2.86 to 20.34), 30-day (OR 3.84, 95 per cent c.i. 1.27 to 11.64), and 90-day (OR 3.73, 95 per cent c.i. 1.19 to 11.70) mortality. Sarcopenia was an independent risk factor for poorer overall survival in multivariate Cox regression analysis (adjusted HR 1.28, 95 per cent c.i. 1.13 to 1.44).
conclusionConsensus-defined sarcopenia provides important prognostic information after elective abdominal surgery and can be appropriately measured in the preoperative setting. Development of targeted exercise-based interventions that minimize sarcopenia may improve outcomes for patients who are undergoing elective abdominal surgery.
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