Evidence mapPaperPMID 37543959Full record

ArticleOphthalmology and therapy2023

Evaluation of the Relationship Between Diabetic Macular Edema and Renal Function in a Latino Population.

José M Torres-Arellano, Andrea Tornero-Jimenez, Alejandra Sánchez-Ríos, Oscar Olvera-Montaño, Patricia Muñoz-Villegas

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Ophthalmology and therapy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05217680 (Phase III Non-inferiority Clinical Study to Evaluate the Efficacy and Safety of Intravitreous PRO-169 Compared to Ranibizumab for Diabetic Macular Edema), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05217680 phase3completednot on this map

Phase III Non-inferiority Clinical Study to Evaluate the Efficacy and Safety of Intravitreous PRO-169 Compared to Ranibizumab for Diabetic Macular Edema

TypeinterventionalSponsorLaboratorios Sophia S.A de C.V.Ran2021 to 2025Enrolled509ConditionsDiabetic Macular EdemaArmsBevacizumab, Lucentis®
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

José M Torres-ArellanoRegional Medical Affairs Department, Laboratorios Sophia, S.A. de C.V., Paseo del Norte 5255, Guadalajara Technology Park, 45010, Zapopan, JAL, Mexico.
Andrea Tornero-JimenezRegional Medical Affairs Department, Laboratorios Sophia, S.A. de C.V., Paseo del Norte 5255, Guadalajara Technology Park, 45010, Zapopan, JAL, Mexico.
Alejandra Sánchez-RíosRegional Medical Affairs Department, Laboratorios Sophia, S.A. de C.V., Paseo del Norte 5255, Guadalajara Technology Park, 45010, Zapopan, JAL, Mexico.
Oscar Olvera-MontañoRegional Medical Affairs Department, Laboratorios Sophia, S.A. de C.V., Paseo del Norte 5255, Guadalajara Technology Park, 45010, Zapopan, JAL, Mexico.
Patricia Muñoz-VillegasRegional Medical Affairs Department, Laboratorios Sophia, S.A. de C.V., Paseo del Norte 5255, Guadalajara Technology Park, 45010, Zapopan, JAL, Mexico. patricia.munoz@sophia.com.mx.ORCID http://orcid.org/0000-0002-7559-1218
Laboratorios Sophia (Mexico) · MXAutonomous University of Aguascalientes · MXUniversidad de Guadalajara · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionDiabetic macular edema (DME) is one of the leading causes of vision impairment. The relationship between DME and estimated glomerular filtration rate (eGFR) has not been clearly evaluated in Hispanic or Latino populations. The objective of this study was to evaluate the eGFR in a Latino population with DME.

methodsA cross-sectional, observational, and descriptive study was carried out on the basis of a multicenter phase III clinical trial.

resultsA total of 82 subjects diagnosed with DME (36 women and 46 men) were included in the study. The mean age was 61.93 ± 6.71 years. Mean values of the blood chemistry parameters glycated hemoglobin and eGFR were 7.20 ± 0.95% and 74.42 ± 26.82 mL/min/1.73 m

conclusionsWe did not find a correlation between eGFR and DME. Our findings suggest that the presence of hypertension is associated with a decrease in the GFR < 60 mL/min/1.73 m

trial registrationNCT05217680 (clinicaltrials.gov).

Indexed as

Central macular thicknessDiabetes mellitusDiabetic macular edemaGlomerular filtration rateTotal macular volume

Identifiers

PMID37543959
PMCPMC10441930
OpenAlexW4385611516

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.