Evidence map›Paper›PMID 37545878›Full record

ArticleFrontiers in cellular neuroscience2023

Differential expression of GABA

Tzu-Hsuan Huang, Yi-Sian Lin, Chiao-Wan Hsiao, Liang-Yun Wang, Musa Iyiola Ajibola, Wahab Imam Abdulmajeed, Yu-Ling Lin, Yu-Jui Li, Cho-Yi Chen, Cheng-Chang Lien and 2 more

Abstract read
In one paragraph

Article in Frontiers in cellular neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Canonical Pathways Rewiring in Alzheimer's Disease.International journal of molecular sciences · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Tzu-Hsuan Huang *Institute of Brain Science, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Yi-Sian Lin *Institute of Biomedical Informatics, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Chiao-Wan Hsiao *Institute of Brain Science, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Liang-Yun WangInstitute of Biomedical Informatics, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Musa Iyiola AjibolaInstitute of Neuroscience, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Wahab Imam AbdulmajeedInstitute of Neuroscience, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Yu-Ling LinInstitute of Neuroscience, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Yu-Jui LiInstitute of Neuroscience, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Cho-Yi ChenInstitute of Biomedical Informatics, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Cheng-Chang LienProgram in Molecular Medicine, National Yang Ming Chiao Tung University and Academia Sinica, Taipei, Taiwan.
Cheng-Di ChiuDepartment of Neurosurgery, China Medical University Hospital, Taichung, Taiwan.
Irene Han-Juo ChengInstitute of Brain Science, National Yang Ming Chiao Tung University, Taipei, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inhibitory γ-aminobutyric acid (GABA)-ergic interneurons mediate inhibition in neuronal circuitry and support normal brain function. Consequently, dysregulation of inhibition is implicated in various brain disorders. Parvalbumin (PV) and somatostatin (SST) interneurons, the two major types of GABAergic inhibitory interneurons in the hippocampus, exhibit distinct morpho-physiological properties and coordinate information processing and memory formation. However, the molecular mechanisms underlying the specialized properties of PV and SST interneurons remain unclear. This study aimed to compare the transcriptomic differences between these two classes of interneurons in the hippocampus using the ribosome tagging approach. The results revealed distinct expressions of genes such as voltage-gated ion channels and GABA

Indexed as

GABAA receptorGABRDparvalbumin (PV)RiboTagRNA-seqsomatostatin (SST)tonic inhibition

Identifiers

PMID37545878
PMCPMC10397515

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.